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曲酸对健康影响的危害评估

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曲酸(Kojic Acid)作为常见的曲霉属和青霉属真菌的代谢产物,存在于传统酿造和发酵食品中,因其具有防腐、保鲜、抗氧化、抗菌、护色和美白等功效,近年来在食品、化妆品和医药等领域广泛应用.本研究参考粮农组织/世界卫生组织食品添加剂联合专家委员会(Joint FAO/WHO Expert Committee on Food Additives,JECFA)关于系统文献检索指南的方法,通过检索数据库以及权威机构网站中与研究相关的文献,获取相关的试验研究及人群流行病学研究等信息,开展曲酸的健康危害评估.
Hazard assessment of the effects of Kojic acid on the health
Kojic acid,as a secondary metabolite commonly produced by many species of filamentous fungi including Aspergillus and Penicillium,exists in traditional brewing and fermented foods.Because of its anti-corrosion,fresh-keeping,anti-oxidation,antibacterial,color protection,whitening effects,it has been widely used in food,cosmetics,medicine in recent years.The health hazard assessment of kojic acid was carried out by referring to JECFA's systematic literature search guidelines,and by searching the research-related literature in the database and the websites of authoritative institutions to obtain the information of experimental studies and population epidemiological studies of substances to be studied.

Kojic acidHazard identificationHazard characterizationHazard assessment

聂燕敏、齐丽娟、宁钧宇、李国君、敬海明、高珊

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北京市疾病预防控制中心,食物中毒诊断溯源技术北京市重点实验室,北京 100013

首都医科大学公共卫生学院,北京 100069

曲酸 危害识别 危害特征描述 危害评估

北京市高层次公共卫生技术人才建设项目

2024

毒理学杂志
北京市预防医学研究中心 北京大学医学部公共卫生学院

毒理学杂志

CSTPCD
影响因子:0.504
ISSN:1002-3127
年,卷(期):2024.38(2)