细菌Na+/H+逆向转运蛋白的研究进展
Research progress of the Na+/H+ antiporters in bacteria
徐宁 1程海娇 2刘清岱 2刘君 1马延和1
作者信息
- 1. 中国科学院天津工业生物技术研究所 天津300308
- 2. 天津科技大学食品工程与生物技术学院 天津300457
- 折叠
摘要
Na+/H+逆向转运蛋白在维持细胞内pH稳态、Na+离子动态平衡和调控细胞体积方面发挥着重要作用.目前,细菌中许多参与高盐或高碱性环境压力应答的Na+/H+逆向转运蛋白得到了鉴定和功能阐释.继续挖掘高效的Na+/H+逆向转运蛋白,深入探究Na+/H+逆向转运蛋白的分子机理,将为工业菌株或农作物的改良提供新的研究思路.本文以4种模式菌株为例,简要概述细菌Na+/H+逆向转运蛋白的种类和特征,同时对其结构和功能等方面也进行探讨.
Abstract
The Na+/H+ antiporters play a primary role in the maintenance of intracellular pH homeostasis and dynamic balance of cellular Na+,and in the regulation of cell volume.Currently,many Na+/H+ antiporter genes involved in the resistance to high salt and alkaline pH stresses have been identified and functionally characterized in various bacteria.The prospection for novel Na+/r+ antiporters from unexplored habitats,in conjunction with our understanding of the mechanisms responsible for Na+/H+ antiport activity,will provide new insights into industrial and agricultural biotechnology.In this review,we chose four physiologically distinct bacteria as examples,and summarized the classification,structure and function of bacterial Na+/H+ antiporters.
关键词
Na+/H+逆向转运蛋白/细菌/种类/功能Key words
Na+/H+ antiporters/Bacteria/Classification/Function引用本文复制引用
基金项目
中国科学院“百人计划”项目()
国家自然科学基金(31500044)
出版年
2015
NETL
NSTL
维普
万方数据