女性上生殖道菌群与妇产疾病的关系:研究进展与展望
Relationship between upper genital tract microbiota and gynecological and obstetric diseases:research progress and prospects
蒋子雯 1王艺璇 2任建 1唐世倩 1靳灵鸽 1张宇迪 1代荫梅 1付钰3
作者信息
- 1. 首都医科大学附属北京妇产医院北京妇幼保健院妇科,北京 100026
- 2. 山东第一医科大学(山东省医学科学院),山东 济南 250117;中国科学院微生物研究所微生物资源前期开发国家重点实验室,北京 100101
- 3. 中国科学院微生物研究所微生物资源前期开发国家重点实验室,北京 100101;中国科学院大学,北京 100049
- 折叠
摘要
在人体内共生的复杂微生物群体具有重要的生理作用,与人体健康的维护和疾病的产生密切相关.近年来,包括女性上生殖道在内的既往被认为无菌的部位,也检测到了微生物的存在.这些菌群是否参与正常的人体生理过程尚不十分明确,但是特定的上生殖道菌群与众多妇产科疾病的发生发展有密不可分的关系.本文将综述女性上生殖道菌群的研究进展,及其与正常生理和女性生殖道疾病的关联.
Abstract
The complex microbiome that resides in the human body plays a crucial physiological role,closely linked to both the maintenance of human health and the onset of diseases.In recent years,microorganisms have been detected in sites previously considered sterile,such as the female upper genital tract.The involvement of these microorganisms in normal physiological processes remains unclear.However,the specific microbiota in the female upper genital tract is strongly correlated with the development of various female diseases.This article reviews the research progress in the microbiota of the female upper genital tract and its associations with normal physiology and genital tract diseases.
关键词
生殖道菌群/微生物组/生殖道疾病/子宫内膜/定殖Key words
genital tract microbiota/microbiome/genital tract diseases/endometrium/colonization引用本文复制引用
出版年
2024
NETL
NSTL
万方数据