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模拟失重对大肠埃希菌生物学性状的影响研究

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研究大肠埃希菌在模拟失重条件下连续传代培养14d后生物学性状的变化.利用Gravite重力控制系统模拟失重条件连续传代培养大肠埃希菌14 d,对菌株的生长速率、形态学、生化代谢、生物膜、环境压力耐受性以及耐药性进行测定,评估模拟失重对大肠埃希菌生物学性状的影响.模拟失重可致大肠埃希菌生长速率增快、体积变小、生化代谢改变、环境压力耐受性及耐药性增加;而相应条件下的生物膜变化无统计学意义.模拟失重可引起大肠埃希菌相关的生物学性状发生变化.
Effects of Simulated Weightlessness on Bio-characteristics of Escherichia coli
The changes of biological characteristics of Escherichia coli after 14 days of subculture under simulated weightlessness conditions were studied.The growth rate,morphology,biochemical metabolism,biofilm,environmen-tal pressure tolerance and drug resistance of Escherichia coli were measured using the Gravite gravity control system under simulated weightlessness conditions for continuous subculture for 14 days.The effects of simulated weightless-ness on the biological characteristics of E.coli were evaluated.The results showed that simulated weightlessness could increase the growth rate of E.coli,reduce its cubage,change its biochemical metabolism,and increase its tolerance to environmental pressure and drug resistance.However,under corresponding conditions the changes of biomembrance has no statistic significance.To conclude,simulated weightlessness can cause changes in correlatively biological char-acteristics of E.coli.

simulated weightlessnessEscherichia colibiological characteristicsgrowth curvedrug resistance

李华娴、韩佩君、刘勇、王文岚

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中国人民解放军空军 军医大学,陕西 西安 710032

模拟失重 大肠埃希菌 生物学性状 生长曲线 耐药性

军队生物安全专项国家自然科学基金项目

A370501200781801995

2024

微生物学杂志
中国微生物学会 辽宁省微生物学会 辽宁省微生物科学研究院

微生物学杂志

CSTPCD北大核心
影响因子:0.964
ISSN:1005-7021
年,卷(期):2024.44(3)