首页|槲皮素的生药资源、药理作用及主要剂型研究进展

槲皮素的生药资源、药理作用及主要剂型研究进展

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槲皮素在植物界分布广泛,在洋葱、莲子、绿茶等食物和五味子、鱼腥草、槐花等中草药中均有较高含量.因槲皮素具有抗氧化、抗炎、抗菌、抗病毒、抗肿瘤、免疫调节和神经保护等多种生物学活性,对动脉粥样硬化、细菌感染、病毒感染、肿瘤、神经系统性疾病的治疗具有十分重要的意义.由于槲皮素具有溶解度低、水溶性差、生物利用度低等特性,限制了其临床应用.药物制剂新技术与新剂型有望攻克槲皮素的应用限制.笔者对槲皮素的生药资源、药理作用和主要剂型研究进展进行了综述.
Research progress on quercetin resource,its pharmacological effect and major dosage form
Quercetin is widely distributed in the plant kingdom.Quercetin is found in high content in foods such as onion,lotus seeds,green tea and Chinese herbal medicine including schisandra,houttuynia and sophora flowers.Quercetin has many biological activities,including anti-oxidation,anti-inflammatory,antibacterial,anti-virus,anti-tumor,immune regulation and neuroprotection.It is of clinical significant in the treatment of atherosclerosis,bacterial infection,viral infection,tumors,nervous system diseases,etc.However,its clinical application is limited due to the low solubility,poor water solubility and low bioavailability.The new technology and dosage forms of pharmaceutical preparations are expected to overcome the application limitation of quercetin.This article provides a brief overview of the crude medicine resources,pharmacological effect,and main dosage form of quercetin.

quercetincrude medicine resourcesdosage formspharmacological effectsbioavailability

张舒宁、叶淳、兰清华、徐艳艳

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浙江中医药大学 药学院,浙江 杭州 310000

丽水市中心医院 药学部,浙江 丽水 323000

槲皮素 生药资源 剂型 药理作用 生物利用度

2025

温州医科大学学报
温州医学院

温州医科大学学报

影响因子:0.762
ISSN:2095-9400
年,卷(期):2025.55(1)