甲状旁腺术中识别技术及临床应用和研究现况
Techniques of identifying parathyroid glands and their related clinical research progress
贺晨宇 1姜可伟1
作者信息
- 1. 北京大学人民医院胃肠外科,北京 100442;北京大学人民医院外科肿瘤研究室、结直肠癌诊疗研究北京市重点实验室,北京 100442
- 折叠
摘要
甲状旁腺在机体钙磷代谢中有重要作用,颈部手术中完整保留甲状旁腺对避免术后甲状旁腺功能减退和术后低钙血症至关重要.目前大多数甲状腺手术中仍依赖传统肉眼识别方式或通过术中冰冻辨认甲状旁腺,前者依赖于术者经验,后者所消耗的时间和费用较高.近年,国内外学者对术中有助于识别甲状旁腺的染色技术和基于荧光的成像技术进行了相关研究,如亚甲蓝、纳米炭、近红外自体荧光、吲哚菁绿血管造影技术、激光散斑对比成像等,均可显著提高对甲状旁腺的识别与保护.本文将对甲状旁腺术中识别技术的临床研究进展情况作一综述.
Abstract
Parathyroid glands play an important role in calcium and phosphorus metabolism in human beings.The complete preservation of parathyroid glands during neck surgery is crucial in avoiding postoperative hypoparathyroidism and hypocalcemia.At present,most thyroid operations still rely on traditional visual identification or intraoperative freezing to identify parathyroid glands.The former depends on the experience of the surgeon,while the latter needs longer time and costs much.Recently,researchers have conducted relevant studies on intraoperative staining techniques and fluorescent-based imaging techniques that are helpful for the identification of parathyroid glands,such as methylene blue,carbon nanoparticles suspension,near-infrared autofluorescence,indocyanine green angiography,and laser speckle contrast imaging.The above-mentioned techniques all have significantly improved the identification and protection of parathyroid glands.This article reviews the progress in clinical research on intraoperative identification of parathyroid glands.
关键词
甲状腺癌根治术/甲状旁腺保护/术中识别Key words
radical surgery of thyroid carcinoma/parathyroid preservation/intraoperative identification引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
维普
万方数据