Changes and influencing factors of pulse wave transit time in hypertensive patients after administration of nifedipine controlled-release tablets
Objective To explore the effect of nifedipine controlled-release tablets on left wrist pulse wave transit time(PWTT)in hypertensive patients.Methods We selected 262 essential hypertensive patients hospitalized at Chinese PLA General Hospital Hainan Branch from August 2021 to December 2022.The patients were divided into observation group(n=140)and control group(n=122)according to whether or not taking nifedipine controlled release tables.The left wrist PWTT at 0.5 h,2.5 h,4.5 h,6.5 h and 8.5 h after administration of the medicine was collected with a smart watch for statistical analysis.Results ①The PWTT in the observation group(93±15,93±13,87±15,85±15,84±10)and the control group(98±18,92±16,90±10,89±8,89±9)decreased gradually with the extension of time(F=11.448,P＜0.001).②The PWTT decreased by the same amplitude(F=2.206,P＞0.05).③There was no significant difference in PWTT between the observation group and the control group at five time points(F=1.164,P＞0.05).Conclusion Administration of nifedipine controlled-release tablets does not affect PWTT of primary hypertensive patients'left wrist.
万方数据
维普
