首页|冠状动脉周围脂肪衰减指数与CT图像重建参数的相关性研究

冠状动脉周围脂肪衰减指数与CT图像重建参数的相关性研究

扫码查看
目的 评估冠状动脉周围脂肪衰减指数(fat attenuation index,FAI)与卷积核、迭代重建算法以及层厚等计算机断层扫描(CT)冠状动脉造影重建参数的相关性.方法 前瞻性纳入44例行CT冠状动脉造影的患者,采用以下3种参数组合进行图像重建:①迭代重建算法(KARL5)和层厚(0.5 mm)不变,采用4种卷积核(Soft_AA、Soft_BA、Soft_CA、Soft_DA,锐利度由低至高)重建;②保持卷积核(Soft_AA)和层厚(0.5 mm)不变,采用滤波反投影(filtered back projection,FBP)和迭代重建算法(KARL5)进行重建;③保持卷积核(Soft_AA)和迭代重建算法(KARL5)不变,采用不同层厚(0.5 mm,1.0 mm)进行重建.经专用分析软件自动提取上述3种参数组合中所有图像的左前降支(left anterior descending artery,LAD)、左回旋支(left circumflex artery,LCX)、右冠状动脉(right coronary artery,RCA)对应的FAI.采用配对t检验、方差分析进行统计分析.结果 对于LAD、LCX和RCA:①不同卷积核间的差异均具有统计学意义(P<0.001),且FAI随卷积核锐利度的提高而降低;②相比于FBP,KARL5重建图像的FAI显著提高(P<0.001);③相比于0.5 mm,1.0 mm层厚图像的FAI均显著降低(P<0.001).结论 卷积核、迭代重建算法及图像层厚对各支冠状动脉的FAI均具有显著影响,临床应用FAI进行诊断时应充分考虑CT重建参数的影响.
Correlation between the pericoronary fat attenuation index and the CT image reconstruction parameters
Objective To evaluate the relationship between the pericoronary fat attenuation index(FAI)and the image reconstruction parameters of computed tomography(CT)coronary angiography,including reconstruction kernel,iterative reconstruction algorithm and image thickness.Methods Forty-four CT coronary angiography scans were prospectively enrolled.All scans were reconstructed by three means as follows:① Four different kernels(Soft_AA,Soft_BA,Soft_CA,and Soft_DA,sharpness from low to high)as the iterative reconstruction algorithm(KARL5)and image thickness(0.5 mm)remained unchanged.② Filtered back projection(FBP)and iterative reconstruction kernel(KARL5)as the kernel and image thickness(0.5 mm)remained unchanged.③ Different image thickness(0.5 mm and 1 mm)as the kernel(Soft_AA)and iterative reconstruction algorithm(KARL5)remained unchanged.The FAI of left anterior descending artery(LAD),left circumflex artery(LCX),and right coronary artery(RCA)was calculated using a dedicated software.Paired t-test and analysis of variance were used for statistical analysis.Results For LAD,LCX and RCA:① The differences of FAI among different reconstruction kernels reached statistical significance(P<0.001),and FAI decreased as the sharper kernel was used.③ Compared with FBP,the FAI of KARL5-reconstructed images significantly increased(P<0.001).③ Compared with 0.5 mm,the FAI of images with 1.0 mm thickness significantly decreased(P<0.001).Conclusion The kernel,iterative reconstruction algorithms,and image thickness all have a significant impact on the FAI of each coronary artery.When using FAI for clinical diagnosis,the effect of CT reconstruction parameters should be taken into account.

coronary arteryatherosclerosiscomputed tomography(CT)reconstruction parameterpcricoronary fat

陈丽虹、陈功婷、樊钢练、李雅楠、屈婷婷、曹乐、荐志洁、郭建新

展开 >

西安交通大学第一附属医院医学影像科,陕西西安 710061

冠状动脉 粥样硬化 计算机断层扫描(CT) 重建参数 冠脉周围脂肪

陕西省重点研发计划项目-一般项目陕西省重点研发计划项目-高校联合项目

2023-YBSF-0682020GXLH-Y-026

2024

西安交通大学学报(医学版)
西安交通大学

西安交通大学学报(医学版)

CSTPCD北大核心
影响因子:1.144
ISSN:1671-8259
年,卷(期):2024.45(4)