冠状动脉周围脂肪衰减指数与CT图像重建参数的相关性研究
Correlation between the pericoronary fat attenuation index and the CT image reconstruction parameters
陈丽虹 1陈功婷 1樊钢练 1李雅楠 1屈婷婷 1曹乐 1荐志洁 1郭建新1
作者信息
- 1. 西安交通大学第一附属医院医学影像科,陕西西安 710061
- 折叠
摘要
目的 评估冠状动脉周围脂肪衰减指数(fat attenuation index,FAI)与卷积核、迭代重建算法以及层厚等计算机断层扫描(CT)冠状动脉造影重建参数的相关性.方法 前瞻性纳入44例行CT冠状动脉造影的患者,采用以下3种参数组合进行图像重建:①迭代重建算法(KARL5)和层厚(0.5 mm)不变,采用4种卷积核(Soft_AA、Soft_BA、Soft_CA、Soft_DA,锐利度由低至高)重建;②保持卷积核(Soft_AA)和层厚(0.5 mm)不变,采用滤波反投影(filtered back projection,FBP)和迭代重建算法(KARL5)进行重建;③保持卷积核(Soft_AA)和迭代重建算法(KARL5)不变,采用不同层厚(0.5 mm,1.0 mm)进行重建.经专用分析软件自动提取上述3种参数组合中所有图像的左前降支(left anterior descending artery,LAD)、左回旋支(left circumflex artery,LCX)、右冠状动脉(right coronary artery,RCA)对应的FAI.采用配对t检验、方差分析进行统计分析.结果 对于LAD、LCX和RCA:①不同卷积核间的差异均具有统计学意义(P＜0.001),且FAI随卷积核锐利度的提高而降低;②相比于FBP,KARL5重建图像的FAI显著提高(P＜0.001);③相比于0.5 mm,1.0 mm层厚图像的FAI均显著降低(P＜0.001).结论 卷积核、迭代重建算法及图像层厚对各支冠状动脉的FAI均具有显著影响,临床应用FAI进行诊断时应充分考虑CT重建参数的影响.
Abstract
Objective To evaluate the relationship between the pericoronary fat attenuation index(FAI)and the image reconstruction parameters of computed tomography(CT)coronary angiography,including reconstruction kernel,iterative reconstruction algorithm and image thickness.Methods Forty-four CT coronary angiography scans were prospectively enrolled.All scans were reconstructed by three means as follows:① Four different kernels(Soft_AA,Soft_BA,Soft_CA,and Soft_DA,sharpness from low to high)as the iterative reconstruction algorithm(KARL5)and image thickness(0.5 mm)remained unchanged.② Filtered back projection(FBP)and iterative reconstruction kernel(KARL5)as the kernel and image thickness(0.5 mm)remained unchanged.③ Different image thickness(0.5 mm and 1 mm)as the kernel(Soft_AA)and iterative reconstruction algorithm(KARL5)remained unchanged.The FAI of left anterior descending artery(LAD),left circumflex artery(LCX),and right coronary artery(RCA)was calculated using a dedicated software.Paired t-test and analysis of variance were used for statistical analysis.Results For LAD,LCX and RCA:① The differences of FAI among different reconstruction kernels reached statistical significance(P＜0.001),and FAI decreased as the sharper kernel was used.③ Compared with FBP,the FAI of KARL5-reconstructed images significantly increased(P＜0.001).③ Compared with 0.5 mm,the FAI of images with 1.0 mm thickness significantly decreased(P＜0.001).Conclusion The kernel,iterative reconstruction algorithms,and image thickness all have a significant impact on the FAI of each coronary artery.When using FAI for clinical diagnosis,the effect of CT reconstruction parameters should be taken into account.
关键词
冠状动脉/粥样硬化/计算机断层扫描(CT)/重建参数/冠脉周围脂肪Key words
coronary artery/atherosclerosis/computed tomography(CT)/reconstruction parameter/pcricoronary fat引用本文复制引用
基金项目
陕西省重点研发计划项目-一般项目(2023-YBSF-068)
陕西省重点研发计划项目-高校联合项目(2020GXLH-Y-026)
出版年
2024
国家科技期刊平台
NSTL
万方数据