西北大学学报(自然科学版)2024,Vol.54Issue(5) :767-784.DOI:10.16152/j.cnki.xdxbzr.2024-05-002

三种秦巴特色中药材的历史沿革与研究进展

The historical evolution and research progresses of three Qinba characteristic Chinese medicinal materials

赵晔 郝晗 耿欣 贾梦辛 张新新 王美 杨洋 李扬 王四旺 郑晓晖
西北大学学报(自然科学版)2024,Vol.54Issue(5) :767-784.DOI:10.16152/j.cnki.xdxbzr.2024-05-002

三种秦巴特色中药材的历史沿革与研究进展

The historical evolution and research progresses of three Qinba characteristic Chinese medicinal materials

赵晔 1郝晗 1耿欣 1贾梦辛 1张新新 2王美 1杨洋 3李扬 1王四旺 4郑晓晖5
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作者信息

  • 1. 西北大学国家中医药管理局中药化学[三级]科研实验室,陕西西安 710069
  • 2. 西安交通大学医学部药学院,陕西西安 710061
  • 3. 陕西师范大学生命科学学院,陕西西安 710119
  • 4. 西北大学陕西省生物医药重点实验室,陕西西安 710069
  • 5. 西北大学陕西省创新药物研究中心,陕西西安 710069
  • 折叠

摘要

秦巴地区特有的气候与水土环境使陕西成为中国生物多样性最丰富的省份之一.陕西自古就是重要的中药材适生区,有"天然药库""秦地无闲草"等美誉,道地中药材有杜仲、秦艽、丹参和黄姜等.道地性的内核是自然环境与生态条件共同演化造就了中药材的性质与功效,为了从千年临床用药经验和研究中全面认识秦巴特色中药材,本研究通过古籍资料考证结合现代研究,选取不同种属3种秦巴特色中药材杜仲、秦艽和黄姜对采收加工、性味归经、炮制提取、化学成分、功效主治、新药研发进行了梳理归纳,探析道地性的物质基础,科学阐释其作用机制,为合理利用、科学开发秦巴特色中药材提供思路,为创新中国药的现代化研发提供源泉.

Abstract

The climate,water and soil environment of Qinba has made Shaanxi one of the provinces with the richest biodiversity in China.Shaanxi has been an important area for the growth of traditional Chinese medi-cine since ancient times,with reputations such as"natural medicine bank"and"no idle grass in Qin land".Authentic traditional Chinese medicine includes Eucommiae cortex,Gentianae macrophyllae radix,Salviae miltiorrhizae radix et rhizoma,and Dioscorea zingiberensis radix et rhizoma.The core of authenticity lies in the co evolution of natural environment and ecological conditions,which have shaped the properties and efficacy of traditional Chinese medicinal materials.In order to comprehensively understand the unique Chinese medicinal materials of Qinba from thousands of years of clinical experiences and research,this article selects three repre-sentative Chinese medicinal materials of Qinba from different genera,studies ancient books and modern re-search,and summarizes their harvesting and preparing,properties and flavors,processing and extraction,chemical composition,efficacy and treatment,and new drug development.It deeply explores the material ba-sis of authentic Chinese medicinal materials,scientifically explains the mechanism of action,provides ideas for the rational use and scientific development of Qinba unique Chinese medicinal materials,and provides a source for the modern research and development of innovative Chinese medicine.

关键词

杜仲/秦艽/黄姜/道地性/秦巴特色中药材/创新中国药

Key words

Eucommiae cortex/Gentianae macrophyllae radix/Dioscorea zingiberensis radix et rhizoma/au-thenticity/unique Chinese medicinal materials of Qinba/innovative Chinese medicine

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出版年

2024
西北大学学报(自然科学版)
西北大学

西北大学学报(自然科学版)

CSTPCD北大核心
影响因子:0.35
ISSN:1000-274X
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