Construction of collagen peptides-ferric pyrophosphate complex and its iron supplementation effect
Iron-loaded complex is a new type of iron fortifying agent that assembles iron ele-ment with food macromolecular.It has the advantages of chemical stability and high bioavail-ability.Through homogenization,ultrasound and dialysis treatment,collagen peptide(CPs)was introduced into the synthesis process of ferric pyrophosphate(FP).The result of FTIR showed that the CPs-FP complex was successfully prepared by this method.The gastrointes-tinal release rate of CPs-FP was higher than that of FP.In the experiment of iron deficiency anemia rats,CPs-FP can effectively improve the body weight,hemoglobin content,tissue iron content and other indexes,showing a concentration-dependent effect.At the same dose,CPs-FP complex exhibited higher bioavailability.