Study on technology and process of room temperature self-strengthening 3D printing of calcium phosphate bioceramic scaffold
In this paper,the 3D printing technology and process of self-strengthening calcium phosphate bioceramics without high temperature post-treatment were developed for the first time without adding polymer binder at room temperature.The scaffolds with different ratios and different printing spacing were studied by material characterization,porosity,mechanical properties test and degradability test.The results show that with the decrease of HA content from 70 wt.％to 50 wt.％,the viscosity and printability of the slurry become worse,and the pore size decreases.The slurry with 60 wt.％HA content has good printability,and the prin-ted scaffold structure is stable and uniform.The compressive strength increased with the de-crease of HA content.The compressive strength of calcium phosphate bioceramic scaffolds printed with 60 w t.％and 50 wt.％HA was 3.61±0.194 MPa(0.6-HTC)and 5.28±0.629 MPa(0.5-HTC),respectively,which could meet the requirements of cancellous bone.In addition,with the increase of printing spacing(1 mm,2 mm and 4 mm),the com-pressive strength of the scaffolds also decreased.With the increase of HA content,the porosi-ty of calcium phosphate bioceramic scaffold increased first and then decreased.The scaffold with 60 wt.％HA content had the largest porosity(51.4％),excellent degradation per-formance and integrity after degradation.This innovative 3D printing technology can directly print and adjust the structure and shape of the stent according to the structural size require-ments of the actual implantation site of the patient at the clinical surgery site,and has great application prospects.
3D printingcalcium phosphate bioceramicscaffoldsmechanical propertiesbiode-gradability
万方数据
维普
