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功能化GNPs在流行病快速检测和实体医疗中的应用

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金纳米粒子(gold nanoparticles,GNPs)与不同分子偶联,不仅可优化其存储条件,还可起放大信号的功能.GNPs是种理想的偶联体,其生物相容性、低毒性、稳定性和表面功能化等特性使其应用具有极强的可塑性.功能化的GNPs为构建体外诊断产品提供了载具基础,在流行病肆虐前期,成熟完善的体外检测方法可提供快速实用和操作便捷的医疗检测.该文就功能化GNPs检测在流行病及医疗诊断中的应用进展进行综述,以期为体外检测和可视化检测等提供借鉴.
Application of Functionalized GNPs in Rapid Epidemic Detection and Physical Medicine
GNPs(gold nanoparticles)coupled with different molecules can not only optimize their storage conditions,but also play a role in amplifying signals.GNPs are excellent conjugates with a very flexible applica-bility due to their biocompatibility,low toxicity,stability and surface functionalization.The functionalized GNPs provide a vehicle basis for the construction of in vitro diagnostic products.A sophisticated and flawless in vitro diagnostic can offer a quick,useful,and easy medical detection system in the early stages of the pandemic.In order to serve a reference for both visual and in vitro detection,this article examines the development of functional GNPs detection in epidemiology and medical diagnosis.

functionalized GNPsin vitro diagnostic productscolorimetric pattern detectionepidemic disease

陈少忠、王冬梅

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福建师范大学生命科学学院,福州 350117

功能化GNPs 体外诊断产品 比色型检测 流行病

2024

中国细胞生物学学报
中国科学院上海生命科学研究院,生物化学与细胞生物学研究所,中国细胞生物学学会

中国细胞生物学学报

CSTPCD
影响因子:0.554
ISSN:1674-7666
年,卷(期):2024.46(2)
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