Advances in Transcriptional Regulation of Spermatogenesis
Transcriptional regulation during spermatogenesis is a complex process.It consists of a series of gene expression and regulatory events that affect sperm formation,quality and function.Transcriptional regulatory mediates the expression of genes including sperm-specific genes,histone genes,and other regulatory factors.The expression and silencing of these genes are regulated by a variety of mechanisms,which includes transcription fac-tors,epigenetic modifications,and non-coding RNA.Furthermore,transcriptional regulation plays different roles in different stages of spermatogenesis,including self-renewal and differentiation of spermatogonia stem cells,meiosis of spermatocytes,and metamorphosis and maturation of sperm cells.Thorough comprehension of transcriptional regulatory mechanisms in spermatogenesis is of great significance for studying the biological processes of sper-matogenesis,resolving the pathological mechanisms of fertility disorders,and developing treatments for fertility problems.
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