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水熊虫超强辐射耐受机制研究进展

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空间辐射损伤是制约人类深空探测及长期在轨驻留的关键医学问题.在多种涉核作业中,超强辐射对人体构成严重危害,对人员健康与安全形成了巨大威胁.水熊虫作为一种独特的多细胞生物,其超强的抗逆能力在生物学研究中备受瞩目.该综述聚焦于水熊虫耐受超强辐射的特性,详细阐述了水熊虫超强辐射耐受机制研究的最新进展,及其在生物医学、辐射防护等领域的意义和潜在应用价值.
Research Progress on the Mechanism of Radiation Tolerance of a Tardigrade
Space radiation damage is a critical medical issue that constrains human deep-space exploration and long-term on-orbit residence.In various nuclear-related work environments,ultra-high radiation poses a severe hazard to human,and a substantial threat to personnel health and safety.Tardigrades,as unique multicellular organ-isms,have attracted considerable attention in biological research for their exceptional stress resistance.This review fo-cuses on the radiation tolerance characteristics of tardigrades,detailing the latest progress in the research on the ultra-high radiation tolerance mechanism of tardigrades,as well as its significance and potential application value in fields such as biomedicine and radiation protection.

tardigradeultra-high radiationmulti-omicstolerance mechanismhorizontal gene transferliquid-liquid phase separation

韦懿芮、李磊、张令强

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军事科学院军事医学研究院,北京 102206

水熊虫 超强辐射 多组学 耐受机制 水平基因转移 液-液相分离

2024

中国细胞生物学学报
中国科学院上海生命科学研究院,生物化学与细胞生物学研究所,中国细胞生物学学会

中国细胞生物学学报

CSTPCD
影响因子:0.554
ISSN:1674-7666
年,卷(期):2024.46(12)