Research progress of tumor-associated macrophages in cervical cancer
Tumor-associated macrophages(TAM)can be differentiated into M1-type and M2-type macrophage phenotypes in the tumor microenvironment(TME),with M2-type macrophages playing a crucial role in malignant tumors.In cervical cancer,TAM exacerbates human papilloma virus(HPV)infection,promotes the proliferation,invasion,and metastasis of tumor cells,stimulates angiogenesis,and induces immune tolerance.TAM targeting strategies have emerged as a hot topic in cervical cancer immunotherapy.
NETL
NSTL
万方数据
