首页|自然杀伤(NK)细胞应对结核分枝杆菌感染的研究进展

自然杀伤(NK)细胞应对结核分枝杆菌感染的研究进展

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结核病(TB)是由结核分枝杆菌(MTB)感染引起的严重威胁人类健康的慢性传染病。自然杀伤(NK)细胞作为先天免疫的重要组成部分,在应对MTB感染时,NK细胞可分化出不同亚群,表现出受体和功能的多样性;并通过分泌细胞因子,串联其他免疫细胞发挥对MTB的抗感染作用,从而增强机体的抗MTB免疫应答反应。
Advances in the study of natural killer(NK)cells'response to Mycobacterium tuberculosis infection
Tuberculosis(TB)is a chronic infectious disease caused by Mycobacterium tuberculosis(MTB)infection and poses a serious threat to human health.Natural killer(NK)cells,an important component of innate immunity,can differentiate into various subpopulations in response to MTB infection,showing a diversity of receptors and functions.They engage in crosstalk with other immune cells by secreting cytokines,thereby exerting anti-infective actions against MTB infection and enhancing the body's immune response to the infection.

NK cellsinfection and immunityNK cell phenotype and receptoranti-tuberculosis immunityreview

任芹、杨国平

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大理大学基础医学院医学微生物学及免疫学教研室,云南大理 671000

自然杀伤(NK)细胞 感染与免疫 NK细胞表型与受体 抗结核免疫 综述

云南省地方本科高校联合专项面上项目大理大学高层次人才资助项目大理大学临床分子免疫学创新团队

2017FH001-085KYBS201708ZKLX2019105

2024

细胞与分子免疫学杂志
中国免疫学会,第四军医大学

细胞与分子免疫学杂志

CSTPCD北大核心
影响因子:0.817
ISSN:1007-8738
年,卷(期):2024.40(7)