Mesenchymal stem cells(MSCs)have the potential for proliferation,multidirectional differentiation and immune regulation.At present,MSCs have been found and isolated from a variety of tissues.Because of their biological characteristics of proliferation,migration and differentiation in vitro,they can be cultured and induced to obtain biologically active cells and their products.More importantly,MSCs also have immunomodulatory functions and play an important role in the treatment of bone injury-related diseases by stem cell transplantation.Therefore,from the perspective of biological characteristics and related functions of MSCs,this article discusses the role of MSCs in osteoimmunity and the mechanism of treatment of bone injury diseases,which will help to fully understand the function of MSCs in physiological and pathological states.
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