中国少数民族MN血型分布
Distribution of MN blood type among China's minority ethnic groups
王文文 1陈萍 2宋奥微 2王文华 2牛佳萌 2邢莉莉 2杨江存 2孙杨 2张超3
作者信息
- 1. 旬邑县医院检验科,陕西咸阳 711300
- 2. 陕西省人民医院输血科,陕西西安 710068
- 3. 汉中市中心血站业务科,陕西汉中 723000
- 折叠
摘要
目的 调查分析中国少数民族MN血型的分布情况.方法 通过系统检索MN血型分布相关文献981篇,筛选出数据完整且符合本研究标准的文献120篇,涵盖49个少数民族.采用SPSS26统计软件对数据进行分析.结果 中国49个少数民族的MN血型表型分布为MN＞MM＞NN,其占比分别42.54％、41.86％、15.06％.MN血型基因频率表现为m＞n,m=0.6313,n=0.3687.通过聚类分析,中国49个少数民族的m基因频率分为3簇,呈现Ⅰ簇＞Ⅱ簇＞Ⅲ簇的特征.结论 中国少数民族MN血型特征表现为m基因频率高于n基因频率;南方少数民族m基因频率高于北方民族;西南少数民族m基因频率与汉族存在显著差异,与汉族长期杂/聚居的少数民族无差异.
Abstract
Objective This study aims to investigate and analyze the distribution of MN blood type among ethnic minorities in China.Methods Through a systematic retrieval of the 981 literature related to MN blood group distribution,120 literature,meeting the criteria of this study,with complete data were selected.The literature covers 49 ethnic minorities.SPSS 26 statistical software was used to analyze the data.Results The results showed that among the 49 ethnic minorities in China,the phenotype distribution of MN blood type was MN＞MM＞NN,with proportions of 42.54％,41.86％,and 15.06％respectively.The gene frequency for MN blood type exhibited a trend of m＞n,with a gene frequency of m being 0.6313 and n being 0.3687.Cluster analysis divided the Chinese ethnic minorities into three groups based on the gene frequency for m,showing the characteristics of Group Ⅰ＞Group Ⅱ＞Group Ⅲ.Conclusion The MN blood type characteristics in Chinese ethnic minorities show a higher frequency of the M gene compared to the N gene.The frequency of the M gene is higher in southern ethnic minorities than in northern ones.There are significant differences between southwestern ethnic minorities and the Han nationality,but no differences with long-term mixed/settled Han populations.
关键词
MN血型/少数民族/基因频率Key words
MN blood group/ethnic minorities/gene frequency引用本文复制引用
出版年
2025
NETL
NSTL
万方数据