Relationship between 24h urinary electrolyte level,urinary sodium potassium ratio and atrial arrhythmia in patients with essential hypertension
Objective To study the relationship between 24h urinary electrolyte level,urinary sodium potassium ratio and atrial arrhythmia in patients with essential hypertension.Methods A total of 703 patients with essential hyper-tension were selected from the Hypertension Center of Xinjiang Uygur Autonomous Region People's Hospital from June 2022 to June 2023.According to the results of holter ECG 24h after admission,the patients were divided into non-atrial arrhythmia group and atrial arrhythmia group.The general clinical and laboratory results of the two groups were com-pared,and the correlation and influencing factors between 24h urinary electrolyte and atrial arrhythmia were analyzed.Results The age and blood sodium levels in the atrial arrhythmia group were higher than those in the non-atrial arrhyth-mia group,while the LVEF,24h urine sodium,24h urine phosphorus and 24h urine magnesium were lower than those in the non-atrial arrhythmia group,the differences were statistically significant(P＜0.05).Spearman correlation analysis showed that the occurrence of atrial arrhythmia was positively correlated with age(ρ=0.389,P＜0.001).It was nega-tively correlated with LVEF,24h urinary sodium,24h urinary phosphorus and 24h urinary magnesium(ρ=-0.127,-0.086,-0.143,-0.091,all P＜0.05).The possible influencing variables were included in the multivariate logistic re-gression analysis,which showed that increased age,increased left atrial diameter,increased urinary calcium at 24h,de-creased left ventricular diastolic diameter,decreased LVEF and decreased triglyceride level were risk factors for atrial ar-rhythmias[OR 95％CI(1.064～1.099),(1.005～1.1.113),(0.888～0.988),(0.873～0.961),(0.760～0.978),(1.027～1.229)]respectively.Conclusion In patients with essential hypertension,the occurrence of atrial arrhythmias is negatively correlated with 24h urinary sodium,24h urinary phosphorus,24h urinary magnesium and LVEF,while age,the increase of left atrial diameter and urinary calcium at 24h,and the decrease of left ventricular diastolic diameter and LVEF may increase the risk of atrial arrhythmia.
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