Effect of Shentong Zhuyu Decoction combined with percutaneous transforaminal endoscopic in the treatment of lumbar disc herniation
Objective To explore the clinical efficacy of Shentong Zhuyu Decoction combined with percutaneous transforaminal endo-scopic in the treatment of lumbar disc herniation(LDH).Methods 60 patients with LDH accepted were randomly grouped into opera-tion group(30 cases)and combined group(30 cases).The patients in the operation group were treated with percutaneous transfo-raminal endoscopic,and the patients in the combined group were treated with Shentong Zhuyu Decoction combined with percutaneous transforaminal endoscopic.The expression of serum interleukin 1β(IL-1β)and CXC chemokine ligand 1(CXCL1),the degree of pain[visual analog scale(VAS)],lower extremity function[(British medical research council,BMRC)lower extremity function score],and the levels of pain mediators[neuropeptide Y(NPY),substance P(SP),and prostaglandin E2(PGE2)]and the efficacy of traditional Chinese medicine(TCM)were compared between the 2 groups.Results The VAS score,serum NPY,SP,PGE2,IL-1β,and CXCL1 levels in both groups were obviously reduced after treatment(P＜0.05),and the combined group is lower than the surgical group(P＜0.05);after treatment,the proportion of BMRC classes 3-4 in the 2 groups was obviously increased(P＜0.05),and compared with the operation group,the combined group was obviously higher(P＜0.05).The total curative effect of the combined group was 96.67%,which was obviously higher than 73.33%of the operation group(P＜0.05).Conclusion Shentong Zhuyu Decoction combined with percutaneous transforaminal endoscopic BEIS technique in treating LDH can effectively relieve pain,reduce the levels of IL-1β and CXCL1,and ameliorate the lower extremity function.
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