首页|门诊骨质疏松症患者药物治疗管理模式的探索

门诊骨质疏松症患者药物治疗管理模式的探索

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目的 评估实施药物治疗管理(medication therapy management,MTM)对骨质疏松症患者用药依从性和症状改善的影响,建立医院MTM服务模式.方法 将258例骨质疏松症患者随机分为干预组和对照组,每组129例.干预组接受常规医疗服务和规范MTM,对照组仅接受常规医疗服务.比较2组患者用药后的骨密度值、骨标志物值、生命质量、疼痛程度、用药依从性和不良反应发生率.结果 干预组患者的骨密度值、骨标志物值、生命质量评分和用药依从性评分均显著高于对照组(P<0.05),疼痛程度评分及不良反应发生率均低于对照组(P<0.05).结论 该院已初步建立了标准化的门诊MTM工作模式,药师主导的MTM服务能有效提高骨质疏松症患者的生活质量和用药依从性,降低了药物不良反应的发生,发挥了临床药师的专业特长,值得深入探索.
Exploration of the medication therapy management model for outpatients with osteoporosis
Objective To explore the effect of medication therapy management(MTM)on medication adherence and symptom improve-ment in patients with osteoporosis,and to establish the medication therapy management services model in hospital.Methods Totally 258 patients with osteoporosis were randomly divided into intervention group and control group,with 129 cases in each group.The patients in the intervention group received routine treatment services and standardized MTM services.The patients in the control group only re-ceived routine treatment services.The bone mineral density(BMD),bone markers,quality of life scores,degree of pain scores,medica-tion compliance scores and adverse drug reaction(ADR)incidence were compared between the 2 groups.Results After treatment,the BMD,bone markers,quality of life scores,medication compliance scores of osteoporosis outpatients in the intervention group were signifi-cantly improved(P<0.05),and the degree of pain scores and adverse drug reaction incidence were reduced when compared with the con-trol group(P<0.05).Conclusion The hospital has preliminarily established its own model of MTM for outpatients.Pharmacists imple-ment MTM service for patients with osteoporosis can improve the quality of life and medication compliance scores,as well as reduce the ADRs incidence.MTM service reflects the pharmacist's professional expertise which needs to be further studied.

medication therapy managementosteoporosispharmacistspharmaceutical services

逯星竹、李永生、毕学苑、潘明明、范婷

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西安交通大学第二附属医院药学部,西安 710004

西安交通大学附属红会医院药学部,西安 710054

西安交通大学附属红会医院骨质疏松科,西安 710054

药物治疗管理 骨质疏松症 药师 药学服务

西安市青年人才托举计划西安市红会医院高层次人才项目医学科研发展基金医学科研发展基金医学科学研究基金

0959202013152021GCCRC09B21114FNB21115FNFY2204

2024

西北药学杂志
西安交通大学,陕西省药学会

西北药学杂志

CSTPCD
影响因子:0.912
ISSN:1004-2407
年,卷(期):2024.39(1)
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