Research progress of anti-epileptic activity succinimide derivatives
Objective To summarize the antiepileptic activity of succinimide derivatives.Methods By gathering relevant information of succinimide derivatives reported in published literatures,the antiepileptic activity and structure-activity relationship(SAR)of succinimide derivatives were summarized.Results The antiepileptic activities of 25 succinimide derivatives were systematically summarized in chrono-logical order.Conclusion Summarizing the activity and SAR of succinimide derivatives lays a foundation for further development of new antiepileptic drugs with succinimide as the parent nucleus.
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