Effect of uterine artery embolization and methotrexate respectively combined with uterine curettage in the treatment of cesarean scar pregnancy
Objective To investigate the application value of uterine artery embolization(UAE)and methotrexate(MTX)respectively combined with uterine curettage in the treatment of cesarean scar pregnancy(CSP).Methods A total of 142 patients with CSP were divided into an observation group(72 patients treated with UAE and uterine curettage)and a control group(70 patients treated with MTX and uterine curettage).The clinical treatments,treatment outcomes,postoperative SF-36 score,and adverse reactions were compared between the 2 groups.Results There was no significant difference in the success rate of conservative treatment,hysterectomy rate or lesion excision rate between the groups(P>0.05).The operation time,intraoperative blood loss,length of hospital stay,recovery time of β-human chorionic gonadotropin(β-hCG),disappearance time of gestational sac,and vaginal bleeding time in the observation group were shorter/less than those in the control group.The hospitalization cost and menstrual recovery time were higher/longer than those in the control group(P<0.05).The observation group had significantly higher SF-36 scores than the control group at 3 and 6 months after treatment(P<0.01).The incidence of adverse reactions in the observation group(4.17%)was lower than that in the control group(15.71%)(P<0.05).Conclusion Uterine artery chemoembolization combined with uterine curettage and methotrexate intramuscular injection combined with uterine curettage can achieve similar curative effect in the treatment of CSP.The former can significantly shorten the operation time,the disappearance time of gestational sac,vaginal bleeding time,and the recovery time of β-hCG,and reduce intraoperative blood loss,with high safety,which is beneficial to the improvement of quality of life,but the hospitalization cost is high.In clinical practice,the 2 conservative treatments can be selected according to the actual situation.
NETL
NSTL
万方数据
维普
