首页|静脉用药调配中心医务人员危害药品职业暴露问题的研究

静脉用药调配中心医务人员危害药品职业暴露问题的研究

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目的 研究静脉用药调配中心医务人员危害药品职业暴露问题。方法 对该院静脉用药调配中心130位医务人员进行调查,收集人员基本资料并采用Logistic多因素回归分析职业暴露危险因素,建立危害药品职业暴露预测模型,并绘制受试者工作特征曲线(receiver operating characteristic,ROC)评估模型预测效果。结果 调查表明,职业暴露发生率为30。77%,护士是重点人群,且以内科较多。Logistic回归分析结果显示,危害药品防护知晓率低、未按照国际标准化流程、未严格执行佩戴防护器具、职业暴露后处理不规范、废弃物处理不当、药品交接不规范、清场和清洁消毒不彻底及复核包装不规范为危害药品职业暴露的独立危险因素(P<0。05)。联合预测因子的ROC曲线下面积为0。710,敏感度为82。50%,特异度为55。56%,表明模型具有较好的预测价值(P<0。05)。结论 临床应对医务人员危害药品应用及处置进行相应培训,以避免或降低职业暴露发生。
Study on the medical personnel's occupational exposure to hazardous drugs in intravenous drug dispensing center
Objective To study the medical personnel's occupational exposure to hazardous drugs in intravenous drug dispensing center.Methods 130 medical staff in intravenous drug dispensing center of a hospital were investigated.The basic data of the subjects were collected and multivariate logistic regression analysis was performed to screen the risk factors for occupational exposure.A prediction model of occupational exposure to hazardous drugs was established,and receiver operating characteristic(ROC)curve was plotted to evaluate the predictive performance of the model.Results The survey showed that the incidence of occupational exposure was 30.77%,and nurses were members of the focus group,most of whom were from the department of internal medicine.Logistic regression analysis showed that low awareness rate of protection from hazardous drugs,failing to operate according to the international standardization process,failing to wear protective device strictly,not standardized treatment after occupational exposure,improper treatment of waste disposal,not standard drug delivery,not complete site-clearing,cleaning and disinfection,and not standard check of packaging were independent risk factors for occupational exposure to hazardous drugs(P<0.05).The sensitivity,specificity and area under ROC curve were 84.00%,68.50%and 0.766,respectively,indicating that the model had good predictive value(P<0.05).Conclusion Clinically,training related to the use and treatment of hazardous drugs should be carried out to avoid or reduce occupational exposure.

intravenous drug dispensing centermedical personnelhazardous drugoccupational exposurerisk factorprevention countermeasure

罗锐、黄钟燕、李红玲

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恩施土家族苗族自治州中心医院健康管理中心,恩施 445000

恩施土家族苗族自治州中心医院脾胃科,恩施 445000

恩施土家族苗族自治州中心医院药学部,恩施 445000

静脉用药调配中心 医务人员 危害药品 职业暴露 危险因素 预防对策

湖北省卫生健康委2019年度第一批联合基金(面上项目)

WJ2019H148

2024

西北药学杂志
西安交通大学,陕西省药学会

西北药学杂志

CSTPCD
影响因子:0.912
ISSN:1004-2407
年,卷(期):2024.39(4)