Influence of oral administration of Tripterygium wilfordii Tablets combined with traditional Chinese medicine fumigation on immune function and peripheral hemogram in patients with rheumatoid arthritis
Objective To investigate the influence of oral administration of Tripterygium wilfordii Tablets combined with traditional Chinese medicine fumigation on immune function and peripheral hemogram in patients with rheumatoid arthritis.Methods 300 patients with rheumatoid arthritis in the hospital were enrolled and divided into observation group and control group by adopting the random number table method,150 cases in each group.The control group was treated with traditional Chinese medicine fumigation,while the observation group was treated with Tripterygium wilfordii Tablets on the basis of the control group.The clinical efficacy,immune function and peripheral hemogram before and after treatment and adverse reactions were compared between the 2 groups.Results After treatment,the observation group(93.33%)had significantly higher total effective rate than the control group(86.00%),P<0.05.After treatment,the levels of immunoglobulin G(IgG),immunoglobulin A(IgA),immunoglobulin M(IgM)and rheumatoid factor(RF)in the observation group were lower than those in the control group(P<0.05).The levels of interleukin-17(IL-17),interleukin-22(IL-22),and tumor necrosis factor-α(TNF-α)in the observation group after treatment were lower than those in the control group(P<0.05).The total incidence rate of adverse events in the observation group(5.33%)was lower than in the control group(12.00%),P<0.05.Conclusion Oral administration of Tripterygium wilfordii Tablets combined with traditional Chinese medicine fumigation is beneficial to enhancing the clinical efficacy,strengthening immune function,improving peripheral hemogram and reducing the incidence rates of adverse reactions in patients with rheumatoid arthritis.
Tripterygium wilfordii Tabletstraditional Chinese medicine fumigationrheumatoid arthritisimmune functionperipheral hemogram
万方数据
维普
