Effect of dexmedetomidine epidural adjuvant intermittent medication on labor analgesia in primiparous women
Objective To investigate the effect of low-dose dexmedetomidine epidural adjuvant intermittent medication on labor pain in primiparous women.Methods 150 primipara were enrolled and randomly divided into control group and study group,with 75 cases in each.The control group was given routine epidural anesthesia,while the study group was given low-dose dexmedetomidine as an auxiliary intermittent epidural medication.The changes of pain perception[visual pain simulation score(VAS)]of the 2 groups before analgesia(t0),30 minutes after analgesia(t1)and after fetal delivery(t2)were recorded respectively.The clinical basic indicators(analgesia time,the amount of anesthetic drugs used and the amount of postpartum hemorrhage)and the duration of each stage of labor(the first stage of labor,the second stage of labor and the third stage of labor)of the 2 groups were compared,and the adverse reactions of the 2 groups were observed.Results The analgesic effect of the study group was higher than that of the control group(P<0.05),and the clinical indicators,the duration of the second and third stages of labor in the study group were lower(shorter)than that of the control group(P<0.05).There was no significant difference between the 2 groups in the length of the first stage of labor and the occurrence of postpartum complications(P>0.05).Conclusion Adjuvant anesthesia with low-dose dexmedetomidine during delivery of primipara can effectively improve the analgesic effect of patients,reduce the dependence of primipara on narcotic drugs,and promote the smooth delivery of primipara.