Predictive factor of failure to induce labor in full-term singleton nulliparous women
Objective:To explore the clinical factors and ultrasound parameters of failed induction of labor in full-term singleton nulliparous women,and to establish a prediction model for failed induction of labor.Methods:The retrospective analysis included a total of 300 pregnant women who gave birth at the Wuxi Maternal and Child Health Care Hospital from Jan-uary 1 2021 to June 30 2021.There were 200 cases in successful induced labor group and 100 cases in failure group.Results:There was no significant difference in age,prenatal weight,ges-tational age,indication for inducing labor and methods of induced labor between the two groups.The height of women in the successful labor induction group was greater than the height of women in the failed labor induction group,the prenatal BMI was lower than the failed group,and the uterine height+abdominal circumference was lower than the failed group(P＜0.05).The proportion of cervical Bishop ≤ 3 points was different between the two groups(P＜0.05).The biparietal diameter+femur length,abdominal circumference,head circumference and esti-mated fetal weight in the successful labor induction group were all lower than those in the failed labor induction group(P＜0.05).Multivariate logistic regression analysis showed that maternal mean stature was the protective factor for failed labor induction(OR=0.82,P＜0.05),esti-mated fetal weight ≥3750g,Bishop score ≤3 points were the risk factors for failed labor induc-tion(OR=1.15,9.41,2.51,P＜0.05).The area under the ROC curve(AUC)of the predic-tion model of failed labor induction was 0.86(95％CI 0.81～0.90),the Youden index was 0.58,the sensitivity was 87％,the specificity was 71％,the prediction accuracy was 81％,and the Hosmer-Lemeshow test was P=0.10.Conclusion:This study successfully screened out four significant influencing factors for the failed induction of labor among primiparas and constructed a prediction model for failed induction of labor,providing a solid theoretical basis to improve the success rate of induction of labor and strongly ensure the safety of mothers and infants.
Failed induction of laborNulliparous womenInfluencing factorPredic-tion model
万方数据
维普
