现代泌尿外科杂志2024,Vol.29Issue(2) :122-125.DOI:10.3969/j.issn.1009-8291.2024.02.006

膀胱大细胞淋巴瘤1例报告并文献复习

Bladder large cell lymphoma:a case report and literature review

汪浩 李步堂 迟辰斐 姜心诚 叶惟靖 陈奇 杨国良 薛蔚
现代泌尿外科杂志2024,Vol.29Issue(2) :122-125.DOI:10.3969/j.issn.1009-8291.2024.02.006

膀胱大细胞淋巴瘤1例报告并文献复习

Bladder large cell lymphoma:a case report and literature review

汪浩 1李步堂 2迟辰斐 2姜心诚 1叶惟靖 2陈奇 2杨国良 2薛蔚2
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作者信息

  • 1. 宁波市杭州湾医院泌尿外科,浙江宁波 315336
  • 2. 上海交通大学医学院附属仁济医院泌尿外科,上海 200135
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摘要

目的 通过分享1例膀胱原发的间变型淋巴瘤激酶(ALK)阴性间变大细胞淋巴瘤(ALK-ALCL)患者在宁波市杭州湾医院泌尿外科和血液科的诊疗过程,提高对ALK-ALCL的认识和诊治水平.方法 回顾性分析该例患者的临床资料和诊疗过程,并结合文献复习探讨该疾病的发病特点、诊治方案和预后.结果 该例患者为青少年男性,以反复肉眼血尿伴右侧腰痛为首发症状,影像学检查显示膀胱肿物,经膀胱肿瘤电切术予以减瘤,同时明确病理为ALK-ALCL,经过化疗及自体造血干细胞移植后患者病情持续缓解,且复查过程中肿瘤未见复发.结论 膀胱原发的ALK-ALCL十分罕见,临床上容易误诊和漏诊,本例患者成功的诊疗经验可供临床参考.

Abstract

Objective To improve the understanding and diagnosis and treatment level of ALK negative anaplastic large cell lymphoma(ALK-ALCL)by sharing the diagnosis and treatment process of a patient with ALK-ALCL treated in Hangzhou Bay Hospital of Ningbo.Methods The clinical data and diagnosis and treatment process of the patient were retrospectively analyzed,and relevant literature was reviewed.Results The patient was a young male,with recurrent gross hematuria and right low back pain as the initial symptoms.Imaging examination indicated bladder tumor.After resection,the tumor was reduced and confirmed to be ALK-ALCL.After chemotherapy and autologous hematopoietic stem cell transplantation,the patient's condition continued to improve.During the follow-up,no recurrence was observed.Conclusion Primary ALK-ALCL in the bladder is very rare and prone to misdiagnosis and missed diagnosis in clinical practice.The successful diagnosis and treatment experience of this patient can provide clinical reference.

关键词

膀胱肿瘤/间变大细胞淋巴瘤/化疗/造血干细胞移植

Key words

bladder tumor/anaplastic large cell lymphoma/chemotherapy/hematopoietic stem cell transplantation

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基金项目

国家自然科学基金(82273288)

出版年

2024
现代泌尿外科杂志
西安交通大学

现代泌尿外科杂志

CSTPCD
影响因子:1.106
ISSN:1009-8291
参考文献量18
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