As an emerging cancer treatment modality,immunotherapy has shown promising efficacy in a variety of solid tumors,but it has failed to achieve a breakthrough in the treatment of prostate cancer.This review aims to provide an overview of the current applications of immunotherapy for prostate cancer,including immune-checkpoint inhibitors,cancer vaccines and chimeric antigen receptor T-cell(CAR-T),briefly describe the mechanisms of various immunotherapy modalities,summarize the results of clinical trials,and discuss the challenges and prospects.