450nm蓝激光汽化术治疗良性前列腺增生患者30例初步经验
Preliminary experience of 450 nm blue laser vaporization in the treatment of 30 patients with benign prostatic hyperplasia
张栋邦 1胡森 1童占表 1马有才 1尚梦蕾 1景钦香1
作者信息
- 1. 青海红十字医院泌尿外科,青海西宁 810000
- 折叠
摘要
目的 分析450 nm蓝激光汽化术治疗良性前列腺增生(BPH)患者的临床效果并总结初步经验.方法 选取2023年6-9月青海红十字医院泌尿外科收治的接受经尿道450 nm蓝激光汽化术治疗的30例BPH患者的临床资料.记录手术操作时间、血红蛋白下降值、膀胱冲洗时间、导尿管留置时间及并发症发生情况.比较患者术前、术后3个月的国际前列腺症状评分(IPSS)、生活质量评分(QoL)、膀胱残余尿量(PVR)和最大尿流率(Qmax)指标变化.结果 患者均顺利完成手术,术中无中转经尿道前列腺电切术(TURP)及开放手术.手术操作时间(38.2±7.5)min,术后24 h血红蛋白下降值(10.4±3.5)g/L,膀胱冲洗时间(15.1±3.3)h,导尿管留置时间(4.5±0.5)d.相较于术前,术后3个月患者的IPSS[(26.28±2.22)分vs.(6.29±2.10)分]、QoL[(5.25±0.85)分 vs.(2.33±0.95)分]、PVR 均显著降低[(397.89±8.47)mL vs.(15.62±2.17)mL],Qmax 显著升高[(8.15±2.09)mL/s vs.(19.50±2.51)mL/s],差异均具有统计学意义(P<0.05).术中膀胱黏膜轻度损伤2例(6.6%),术后二次留置导尿管1例(3.3%),术后肉眼血尿1例(3.3%),未发生严重并发症.结论 采用450 nm蓝激光汽化术治疗BPH患者具有快速高效、止血可靠、并发症低的优点,可有效改善患者排尿情况,值得临床推广应用.
Abstract
Objective To analyze the clinical efficacy of 450 nm blue laser vaporization in the treatment of benign prostatic hyperplasia(BPH)and to summarize the preliminary experience.Methods Clinical data of 30 BPH patients who underwent transurethral 450 nm blue laser vaporization at our hospital during Jun.and Sep.2023 were selected.The operation time,hemoglobin decrease value,bladder irrigation time,catheterization time,and incidence of complications were recorded.The changes in the international prostate symptom score(IPSS),quality of life score(QoL),postvoid residual(PVR)volume,and maximum urinary flow rate(Qmax)were compared before and 3 months after surgery.Results All operations were successfully completed without conversion to transurethral resection of the prostate(TURP)or open surgery.The operation time was(38.2±7.5)minutes,the hemoglobin decrease value was(10.4±3.5)g/L 24 hours after surgery,the bladder irrigation time was(15.1±3.3)hours,and the catheterization time was(4.5±0.5)days.Compared to preoperative,3 months after surgery,the IPSS[(26.28±2.22)vs.(6.29±2.10)],QoL[(5.25±0.85)vs.(2.33±0.95)],and PVR were decreased[(397.89±8.47)mL vs.(15.62±2.17)mL],while the Qmax was increased[(8.15±2.09)mL/s vs.(19.50±2.51)mL/s],with statistical significance(P<0.05).Mild bladder mucosal injury occurred in 2 cases(6.6%)during surgery,a second indwelling catheter was placed in 1 case(3.3%)after surgery,and gross hematuria occurred in 1 case(3.3%)after surgery.No serious complications occurred.Conclusion The use of 450 nm blue laser vaporization for the treatment of BPH has advantages of fast,efficient and reliable hemostasis,and low incidence of complications,which can effectively improve urination and is worthy of clinical promotion and application.
关键词
良性前列腺增生/450nm蓝激光/经尿道前列腺电切术/前列腺汽化切除Key words
benign prostatic hyperplasia/450 nm blue laser/transurethral resection of the prostate/prostate vaporization resection引用本文复制引用
基金项目
青海省卫生健康委指导性计划(2021-wjzdx-63)
出版年
2024