儿童膀胱尿路上皮肿瘤1例报告并文献复习
Bladder urothelial carcinoma in children:a case report and literature review
努尔艾力·排尔哈提 1朱新胜 1李卫华 1王令令 1展昭兴 1艾力亚尔·艾尼瓦尔1
作者信息
- 1. 喀什地区第二人民医院泌尿外科,新疆喀什 844000
- 折叠
摘要
目的 探讨儿童膀胱尿路上皮肿瘤(BUC)的临床病理特点,分享诊疗经验.方法 报告喀什地区第二人民医院泌尿外科收治的1例罕见的9岁男性BUC患儿的临床病历资料和诊疗过程,并进行文献复习.结果 患儿主诉血尿.术前经腹部泌尿系超声、计算机断层扫描尿路成像(CTU)发现BUC,予以全身麻醉下行经尿道膀胱尿路上皮肿瘤钬激光剜除术,术后病理提示膀胱低恶性潜能的乳头状尿路上皮肿瘤,术后给予盐酸表柔比星膀胱灌注化疗,随访3个月未发现肿瘤进展或复发.结论 儿童BUC在临床上十分罕见,血尿是该病最常见的临床症状,一般无特异性阳性体征.经腹泌尿系超声是首选的影像学检查手段,手术治疗是最佳途径,目前尚无可推荐的膀胱灌注化疗方案,术后需要进行长期严格的随访.
Abstract
Objective To analyze the clinicopathological features of bladder urothelial carcinoma BUC in children and to share the experience of diagnosis and treatment.Methods The clinicopathological data,diagnosis and treatment process of a rare 9-year-old boy with BUC treated in the Second People's Hospital of Kashgar were reported and the literature was reviewed.Results The main clinical symptom is hematuria.Both preoperative urinary ultrasound and CT urography(CTU)identified the tumor,which was then removed with transurethral holmium laser resection under general anesthesia.Postoperative pathology confirmed papillary urothelial neoplasm of low malignant potential(PUNLMP).Epirubicin hydrochloride instillation was administered,and no evidence of recurrence or progress was detected during the 3-month follow-up.Conclusion Bladder urothelial carcinoma in children is extremely rare.The most common symptom is hematuria,and there are no characteristic signs.Urinary ultrasound is the first choice for preoperative imaging,and transurethral resection of the carcinoma results in good recovery.There is no recommendable instillation,and patients need long-term postoperative follow-up.
关键词
儿童/血尿/膀胱尿路上皮肿瘤/低恶性潜能的乳头状尿路上皮肿瘤/膀胱灌注化疗Key words
child/hematuria/bladder urothelial carcinoma/papillary urothelial neoplasm of low malignant potential/bladder instillation引用本文复制引用
出版年
2024
NETL
NSTL
万方数据