摘要
目的 对比经尿道前列腺蓝激光汽化切除术与经尿道前列腺电切术(TURP)治疗良性前列腺增生(BPH)的临床疗效及安全性.方法 回顾性分析2023年1-8月在泰安市中心医院迎胜院区泌尿肾病激光治疗中心接受手术治疗的142例BPH患者的临床资料.根据不同手术方式将患者分为蓝激光组(n=72)行经尿道前列腺蓝激光汽化切除术、电切组(n=70)行TURP.比较两组患者手术时间、血红蛋白(Hb)下降量、膀胱冲洗时间、尿管留置时间、术后住院时间.比较两组患者术前及术后6个月国际前列腺症状评分(IPSS)、生活质量评分(QoL)、最大尿流率(Qmax)、膀胱残余尿量(PVR)、国际勃起功能专项评分(IIEF-5)及并发症发生率.结果 两组患者术后6个月的IPSS、QoL、Qmax、PVR均较术前有显著改善(P＜0.05),但组间差异无统计学意义(P＞0.05).蓝激光组和电切组患者手术时间[(25.46±5.84)min vs.(47.04l±4.03)min]、膀胱冲洗时间[(21.18±4.11)h vs.(54.17±4.99)h]、尿管留置时间[2(2,2)d vs.5(5,6)d]、术后住院时间[4(3,4)d vs.7(7,8)d]、Hb 下降量[(4.31±2.34)g/L vs.(9.61±2.16)g/L]及并发症总发生率(4.2％vs.51.4％)比较,蓝激光组明显低于电切组,而蓝激光组术后6个月IIEF-5高于电切组[(20.06±2.13)分vs.(18.93±1.85)分],差异均有统计学意义(P＜0.05).结论 经尿道前列腺蓝激光汽化切除术与TURP均可有效治疗BPH,但前者疗效更确切,康复时间更短,并发症更少,对患者性功能影响更小,是一种安全、有效的微创手术方式.
Abstract
Objective To compare the clinical efficacy and safety of transurethral blue laser vaporization of prostate and transurethral resection of prostate(TURP)in the treatment of benign prostatic hyperplasia(BPH).Methods The clinical data of 142 BPH patients undergoing surgery in our hospital during Jan.and Aug.2023 were retrospectively analyzed.The patients were divided into blue laser group(n=72)and TURP group(n=70).The operation time,hemoglobin(Hb)decrease,bladder irrigation time,catheter indwelling time and postoperative hospital stay were compared between the two groups.The changes of international prostate symptom score(IPSS),quality of life score(QoL),maximum urinary flow rate(Qmax),postvoid residual volume(PVR),international index of erectile function-5(IIEF-5)score and complications before and 6 months after operation were also compared.Results Six months after operation,the IPSS,QoL,Qmax and PVR were significantly improved in both groups(P＜0.05),but there were no significant differences between the two groups(P＞0.05).Compared with the TURP group,the blue laser group had shorter operation time[(47.04±4.03)min vs.(25.46±5.84)min],shorter postoperative bladder irrigation time[(54.17±4.99)h vs.(21.18±4.11)h],shorter catheter indwelling time[5(5,6)d vs.2(2,2)d],shorter postoperative hospital stay[7(7,8)d vs.4(3,4)d],less Hb decrease[(9.61±2.16)g/L vs.(4.31±2.34)g/L],and lower incidence of complications(51.4％vs.4.2％),with significant differences(P＜0.05).Six months after surgery,the blue laser group had higher IIEF-5 score than that the TURP group[(20.06±2.13)vs.(18.93±1.85)],with significant difference(P＜0.05).Conclusion Both transurethral blue laser vaporization of prostate and TURP can effectively treat BPH,but the former is more effective,for it has advantages of short recovery time,few complications and small impact on the sexual function of patients.
维普
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