Renal colic caused by ureteral stone obstruction is the main cause for emergency treatment of patients with urinary tract stones,and drug expulsion therapy plays a vital role in the treatment.This article delves into a variety of drugs,including α1 adrenergic receptor blockers,β adrenergic receptor agonists,calcium channel blockers,prostaglandin synthetase inhibitors,corticosteroids,phosphodiesterase isoenzyme 5 inhibitors,and Chinese herbal medicines,exploring their mechanisms and applications in the treatment of distal ureteral stones.Currently,α1 adrenergic receptor blockers are still preferred for the treatment of distal ureteral stones due to their significant efficacy.It is worth noting that various drugs work through different mechanisms,and combining drugs with different mechanisms is expected to improve the efficiency of stone expulsion.This method may become the mainstream choice for stone expulsion drugs in the future.This article aims to provide new perspectives and ideas for the drug treatment of urinary tract stones.
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