Analysis of the correlation between patients with inflammatory bowel disease and metabolic syndrome
Objective Exploring the correlation between inflammatory bowel disease and metabolic syndrome.Methods Ninety-seven patients with ulcerative colitis(UC)and 63 patients with Crohn's disease(CD)attending the People's Hospital of Xinjiang Uygur Autonomous Region from January 2020 to August 2023 were selected as the case group,and 320 healthy medical checkups coming to the hospital during the same period were selected as the control group.The general condition,and the results of related tests and examinations were collected from all the study subjects.The data were collated,the body mass index(BMI)and the number of MS groups were calculated,the incidence of metabolic associated fatty liver disease(MAFLD)and MS was counted,and the relationship between UC and CD patients and the above general factors and MS-related indexes was analyzed.We also analyzed the relationship between patients with UC and CD and the above general factors and MS-related indexes.Results The rates of combined hypertension,diabetes mellitus and MAFLD were significantly higher in patients in both the UC and CD groups than in the control group(P＜0.05).Multifactorial logistic regression analysis showed a degree of correlation between the levels of MS-related indicators and IBD.Specifically,history of hypertension,history of diabetes,triglycerides,high-density lipoprotein,low-density lipoprotein,diastolic blood pressure,and BMI were associated with the risk of developing UC(P＜0.05);history of diabetes,high-density lipoprotein,low-density lipoprotein,and systolic blood pressure were associated with the risk of developing CD(P＜0.05).Conclusion There is a correlation between the levels of MS-related indicators and IBD,and the incidence of MS is higher in patients with IBD.Healthy people should reduce the incidence of co-morbidities of IBD and MS and improve the quality of life by promoting a scientific lifestyle,rational diet,and weight control.
万方数据
维普
