Clinical application of ascorbic acid combined with compound polyethylene glycol electrolyte powder in bowel preparation of patients
Objective To compare the efficacy and safety of ascorbic acid combined with 2L polyethylene glycol electrolyte powder and 3L polyethylene glycol electrolyte powder in bowel preparation of patients.Methods A total of 200 outpatients receiving colonoscopy in the First Affiliated Hospital of Anhui University of Science and Technology(Huainan First People's Hospital)from November 2023 to May 2024 were selected as the study objects,and the patients were divided into control group and experimental group by random number table method,with 100 cases in each group.Among them,the control group received 3L polyethylene glycol electrolyte powder,and the experimental group received 2L polyethylene glycol electrolyte powder and 4g ascorbic acid.The relevant data of bowel cleaning effect,lesion detection rate,first defecation time,catheter entry time,catheter exit time,defecation frequency,incidence of adverse reactions,compliance,satisfaction and willingness to repeat examination were compared between the two groups.Results There was no significant difference in the total score of Boston Intestinal Readiness Scale and the scores of right colon,transverse colon and left colon between the two groups(P＞0.05).The rate of lesion detection in the experimental group was higher than that in the control group,and the difference was statistically significant(P＜0.05).There was no significant difference in the time of first defecation,entry time and exit time between the two groups(P＞0.05).The frequency of defecation in the control group was more than that in the experimental group,and the difference was statistically significant(P＜0.05).Patients'satisfaction,compliance and willingness to repeat examination in the experimental group were higher than those in the control group,the difference was statistically significant(P＜0.05),and the incidence of adverse reactions in the experimental group was lower than that in the control group,the difference was statistically significant(P＜0.05).Conclusion The effect of ascorbic acid combined with 2 L polyethylene glycol electrolyte powder on intestinal cleaning is not worse than that of 3 L polyethylene glycol electrolyte powder.At the same time,it can improve the detection rate of lesions,reduce the total amount of liquid taken by patients,reduce the incidence of adverse reactions,improve patients'compliance,satisfaction and willingness to repeat examination.It is a promising intestinal cleaning drug.
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