In a variety of social environments,due to psychological,physiological,environmental,academic,social and other factors,the student stress has increased dramatically.In order to find the main causes of student stress and solve the problem of excessive student stress,this paper selects the dataset of multiple factors affecting student stress,uses the Apriori algorithm to research the influence situation of multiple factors related to student stress,and analyzes the frequent item sets and association rules of different factors and stress,then finds that anxiety problems,sleep problems,environmental safety,bullying and other problems have a great impact on student stress.Research results show that reducing academic stress,resisting bullying and improving the living environment of students can help reduce student stress.