首页|基于CT特征追踪技术评估慢性心力衰竭左心室心肌应变的初步研究

基于CT特征追踪技术评估慢性心力衰竭左心室心肌应变的初步研究

A study on CT feature tracking in evaluating left ventricular myocardial strain in chronic heart failure

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目的 探讨基于CT特征追踪技术评估慢性心力衰竭(CHF)左心室心肌应变的价值.方法 选取2021年6月至2022年5月在衢州市中医医院就诊的53例CHF患者为CHF组,另选取同期本院体检的50名年龄相匹配的健康者为对照组.所有研究对象接受冠状动脉CT血管成像(CCTA)和心脏磁共振(CMR)检查获取左心室心功能参数[包括左心室收缩末期容积(LVESV)、左心室舒张末期容积(LVEDV)、左心室每搏出量(LVSV)、左心室射血分数(LVEF)]和心肌应变参数[包括全局径向峰值应变(GPRS)、纵向峰值应变(GPLS)、周向峰值应变(GPCS)],比较两组研究对象CCTA测得的心功能参数和心肌应变参数,采用Pearson相关分析CHF患者CCTA测得的心肌应变参数与心功能参数的相关性,比较CHF患者CCTA与CMR测得的心功能参数和心肌应变参数,验证CCTA与CMR测得的心肌应变参数一致性.结果 CHF组LVSV、LVEF、GPRS均明显低于对照组(均P<0.01),LVESV、LVEDV、GPCS、GPLS均明显高于对照组(均P<0.01).CHF患者GPRS与LVSV、LVEF均呈正相关(均P<0.01),与LVESV、LVEDV均呈负相关(均P<0.01);GPCS、GPLS与LVSV、LVEF均呈负相关(均P<0.01),与LVESV、LVEDV均呈正相关(均P<0.01).CHF患者CCTA测得的LVSV明显低于CMR测量结果,CCTA测得的LVESV、LVEDV、GPRS均明显高于CMR测量结果,差异均有统计学意义(均P<0.05);两种方法测得的LVEF、GPCS、GPLS比较,差异均无统计学意义(均P>0.05).CCTA与CMR测得的GPCS、GPLS具有良好的一致性,而GPRS的一致性较差.结论 基于CT特征追踪技术评估CHF左心室心肌应变具有一定的可行性,与CMR测量结果的一致性较好.
Objective To investigate the value of CT feature tracking in evaluating left ventricular myocardial strain in chronic heart failure(CHF).Methods Fifty-three CHF patients treated at Quzhou Traditional Chinese Medicine Hospital from June 2021 to May 2022 were selected as CHF group,and 50 age-matched healthy people who underwent physical examination at the same time were selected as control group.All subjects underwent coronary CT angiography(CCTA)and cardiac magnetic resonance(CMR)to obtain left ventricular function parameters[including left ventricular end-systolic volume(LVESV),left ventricular end-diastolic volume(LVEDV),left ventricular stroke volume(LVSV),left ventricular ejection fraction(LVEF)]and myocardial strain parameters[including global peak radial strain(GPRS),global peak longitudinal strain(GPLS),global peak circumferential strain(GPCS)].The cardiac function parameters and myocardial strain parameters measured by CCTA were compared between the two groups.Pearson correlation was used to analyze the correlation between myocardial strain parameters and cardiac function parameters measured by CCTA,and the cardiac function parameters and myocardial strain parameters measured by CCTA and CMR in CHF patients were compared.The consistency of myocardial strain parameters measured by CCTA and CMR was verified.Results LVSV,LVEF and GPRS in CHF group were significantly lower than those in the control group(all P<0.01),while LVESV,LVEDV,GPCS and GPLS were significantly higher than those in the control group(all P<0.01).GPRS was positively correlated with LVSV and LVEF(both P<0.05),and negatively correlated with LVESV and LVEDV(both P<0.01).GPCS and GPLS were negatively correlated with LVSV and LVEF(all P<0.01),and positively correlated with LVESV and LVEDV(all P<0.01).LVSV measured by CCTA was significantly lower than that measured by CMR(P<0.01).LVESV,LVEDV,and GPRS measured by CCTA were significantly higher than those measured by CMR(all P<0.05).There was no significant difference in LVEF,GPCS,and GPLS measured by the two methods(all P>0.05).GPCS and GPLS measured by CCTA and CMR had good consistency,while the consistency of GPRS is poor.Conclusion It is feasible to evaluate left ventricular myocardial strain in CHF based on CT feature tracking,which is in good agreement with CMR measurement results.

Chronic heart failureCoronary CT angiographyFeature trackingMyocardial strain

夏花、孙俊、徐升

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324000 衢州市中医医院放射科

慢性心力衰竭 冠状动脉CT血管成像 特征追踪 心肌应变

衢州市指导性科技攻关计划

2022045

2024

心电与循环
浙江省医学会

心电与循环

影响因子:0.269
ISSN:2095-3933
年,卷(期):2024.43(2)
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