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颅内动脉粥样硬化性狭窄介入治疗研究进展

Research progress in interventional therapy for intracranial atherosclerotic stenosis

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颅内动脉粥样硬化性狭窄(ICAS)是导致缺血性卒中的重要原因之一.ICAS患者的卒中复发风险较高,血管内治疗通常被用于药物治疗控制欠佳的ICAS患者,但目前已发表的临床试验并未证明介入治疗相较于最佳药物治疗在ICAS治疗中的优越性,因此ICAS介入治疗仍然是悬而未决的研究热点.本文从ICAS介入治疗器械和策略、既往临床试验回顾、适用人群争议等方面展开,就ICAS介入治疗研究进展作一述评.
Intracranial atherosclerotic stenosis(ICAS)is one of the leading causes of ischemic stroke worldwide.Patients with ICAS possess a high risk of stroke recurrence.Endovascular treatment is employed to manage ICAS patients who have a high likelihood of recurrent stroke despite undergoing the best medical therapy.Nevertheless,published trials fail to demonstrate the superiority of interventional therapy over best medical therapy in ICAS patients.The treatment options for ICAS are still under debate.This commentary focuses on devices and strategies,published clinical trials,and applicable populations regarding interventional therapy for ICAS,and aims to summarize the progress in this research hotspot.

Acute ischemic strokeIntracranial atherosclerotic stenosisEndovascular treatmentClinical research

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310006 杭州,浙江大学医学院附属第一医院神经内科

缺血性卒中 颅内动脉粥样硬化性狭窄 血管内治疗 临床研究

2024

心电与循环
浙江省医学会

心电与循环

影响因子:0.269
ISSN:2095-3933
年,卷(期):2024.43(5)