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不同浓度医用三氧对肛肠术后创面愈合的影响

Effects of different concentrations of medical trioxygen on wound healing after anorectal surgery

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目的 观察不同浓度医用三氧对肛肠科术后患者创面愈合的临床效果.方法 选取2023年1-12月医院收治并已进行手术的肛周坏死性肌筋膜炎或低位肛瘘或环状混合痔患者共129例.按照组间年龄、病程、病种等基线资料组间均衡可比的原则分为A、B、C三组,各43例.三组患者手术方法相同,术后处理中的医用三氧浓度分别为20、40、80mg/L.比较三组患者的术后视觉模拟疼痛评分(VAS)、水肿评分、创面愈合率及临床疗效.结果 术后第2天、第7天、第15天,三组患者的VAS评分均逐渐降低,其中A组最高,B组最低,组间差异具有统计学意义(P<0.05).术后第7天,三组患者的水肿情况、创面愈合率比较,差异无统计学意义(P>0.05);术后第15天,三组患者水肿情况均有所改善,但B组改善的比例优于A组和C组(P<0.05);术后第15天和第21天时创面愈合率均逐渐升高,B组患者愈合率明显高于A、C两组(P<0.05).治疗结束后三组患者均有一定的临床疗效,但A组总有效率最低,B组最高,差异有统计学意义(P<0.05).结论 中等浓度(40mg/L)医用三氧在肛肠术后患者创面疼痛、水肿、创面愈合率及临床疗效方面表现出较好的优势,且具有较高的安全性.
Objective The clinical effect of different concentrations of medical trioxygen on the wound healing of patients after anorectal surgery was observed.Methods A total of 129 patients with perianal necrotizing myofasciitis or low anal fistula or ring mixed hemorrhoids who were admitted to hospitals from January to December 2023 were selected.According to the principle of age,disease course,disease type and other baseline groups,they were divided into groups A,B and C,with 43 cases each.The three groups had the same surgical procedure,and the medical trioxygen concentration in the postoperative treatment was 20,40,and 80 mg/L,respectively.The operative visual analogue pain score(VAS),edema score,and wound healing rate were compared in the three groups.Results The VAS scores between the three groups(P>0.05);the VAS scores between postoperative day 7 and 15,and statistically significant(P<0.05).At 15 days after surgery,the resolution of the edema was most pronounced in patients with moderate concentrations.No edema in the three groups(P>0.05)and postoperative day 15(P<0.05).With the extension of treatment time,the wound healing rate of the three groups was increasing,at the 7,15 and 21 postoperative days(P<0.05).At 21 days after surgery,the group showed good clinical advantage,followed by high concentration,and the effect of low concentration was relatively weak.Conclusion Moderate concentration(40 mg/L)medical trioxygen showed good advantages in wound pain,edema,wound healing rate and clinical efficacy in patients after anorectal surgery,and has a high safety profile.

Different concentrationsMedical ozoneWound healing

黎娜、黄晓静

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563000 贵州省遵义市第一人民医院(遵义医科大学第三附属医院)

不同浓度 医用三氧 创面愈合

2024

现代养生
河北省医疗气功医院

现代养生

影响因子:1.355
ISSN:1671-0223
年,卷(期):2024.24(24)