Pathogenic and clinical characteristics of 7 cases of double bacterial hepatic abscess
Objective To explore the pathogenic and clinical characteristics of 7 cases of double bacteri-al hepatic abscess.Methods The clinical data of 7 cases of double bacterial hepatic abscess treated in this hos-pital from January 2015 to December 2021 were analyzed retrospectively.The bacterial spectrum,clinical man-ifestations and complications were analyzed,and the clinical characteristics of double mixed bacterial hepatic abscess were summarized.Results In 7 cases of double mixed bacterial hepatic abscess,the age was 22.0-78.0 years old,the mean age was(58.9+17.7)years old,the mean hospital stay time was(15.6±10.9)d.Six cases(85.7％)were complicated with underlying disease and previous surgical history.Fever(71.4％)and abdominal pain(57.1％)were the main symptoms.Pneumonia and pleural effusion were the main complica-tions.The mean diameter of hepatic abscess was(6.1±3.2)cm,and all patients were cured by percutaneous puncture and drainage of hepatic abscess combined with antibiotics for anti-infection treatment.All patients had varied degree of liver function injury.The main pathogenic bacteria were Klebsiella pneumoniae and Esch-erichia coli.The proportions of cephalosporin and quinolone antibiotic resistance all were 57.1％(4/7),and carbopenem antibiotic resistance proportion was 28.6％(2/7).Conclusion Double mixed hepatic abscess usu-ally occurs in the elderly patients with complicating underlying disease and previous surgical history.Klebsiel-la pneumoniae and Escherichia coli are main pathogenic bacteria,moreover which are easy to have drug resist-ance.
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