Relationship between body mass index and resting heart rate at admission in patients with coronary heart disease
Objective To assess the relationship between the body mass index(BMI)and the resting heart rate(RHR)at admission in the patients with coronary heart disease(CHD).Methods The original da-ta of 2 533 patients with CHD in Shenzhen Municipal People's Hospital.The univariate and multivariate re-gression models were used to evaluate the relationship between BMI and RHR,and in order to determine the association between BMI and RHR,the stratified analysis and interaction tests were conducted.Lastly,the re-lationship between BMI and RHR was investigated by the smooth curve fitting after adjusting the potential confounding factors.Results BMI was negatively correlated with RHR at admission(adjusted β=-0.50,95%CI-0.67--0.33,P<0.001).Using the lowest group of BMI as the reference,RHR was decreased with the increase of BMI(a=-1.96,95%CI-3.55--0.37,P=0.016;β=-3.45,95%CI-5.13--1.76,P<0.001,and β=-5.35,95%CI-7.13--3.57,P<0.001),trend test P<0.001.However,a nonlinear relationship existed between BMI and RHR.The regression coefficient was-0.70(95%CI-0.93--0.48,P<0.001)after BMI<27.6 kg/m2 adjustment,while which was 0.11(95%CJ-0.37-0.59,P=0.649)for BMI ≥27.6 kg/m2.Conclusion BMI has significantly negative correlation with RHR at admission in the patients with CHD,and the saturation effect exists.
Body mass indexObesityHeart rateCoronary heart disease