首页|冠心病患者入院体重指数与静息心率的关系研究

冠心病患者入院体重指数与静息心率的关系研究

扫码查看
目的 评估冠心病患者入院体重指数(BMI)与静息心率(RHR)的关系。方法 收集深圳市人民医院2018年1月至2021年12月2 533例冠心病患者的原始数据。排除BMI(n=914)、入院时RHR(n=155)变量数据缺失及其他协变量缺失资料(n=122)的患者,最终纳入1 342例冠心病患者。采用单变量和多变量回归模型评价BMI和RHR之间的关系,为了确定BMI和RHR之间的关联,进行分层分析和交互检验,最后通过调整潜在混杂因素后的平滑曲线拟合探讨BMI和RHR之间的关系。结果 BMI与入院时的RHR呈负相关(校正后的β=-0。50,95%CI-0。67~-0。33,P<0。001)。以BMI的最低组作为参考,RHR随着BMI 的增加而下降(β=-1。96,95%CI-3。55~-0。37,P=0。016;β=-3。45,95%CI-5。13 1。76,P<0。001;β=-5。35,95%CI-7。13~-3。57,P<0。001),趋势性检验 P<0。001。然而,BMI 和 RHR 之间存在非线性关系。BMI<27。6 kg/m2 调整后的回归系数为-0。70(95%CI-0。93~-0。48,P<0。001),而 BMI≥27。6 kg/m2则为0。11(95%CI-0。37~0。59,P=0。649)。结论 在冠心病患者入院时,BMI与RHR呈显著负相关,存在饱和效应。
Relationship between body mass index and resting heart rate at admission in patients with coronary heart disease
Objective To assess the relationship between the body mass index(BMI)and the resting heart rate(RHR)at admission in the patients with coronary heart disease(CHD).Methods The original da-ta of 2 533 patients with CHD in Shenzhen Municipal People's Hospital.The univariate and multivariate re-gression models were used to evaluate the relationship between BMI and RHR,and in order to determine the association between BMI and RHR,the stratified analysis and interaction tests were conducted.Lastly,the re-lationship between BMI and RHR was investigated by the smooth curve fitting after adjusting the potential confounding factors.Results BMI was negatively correlated with RHR at admission(adjusted β=-0.50,95%CI-0.67--0.33,P<0.001).Using the lowest group of BMI as the reference,RHR was decreased with the increase of BMI(a=-1.96,95%CI-3.55--0.37,P=0.016;β=-3.45,95%CI-5.13--1.76,P<0.001,and β=-5.35,95%CI-7.13--3.57,P<0.001),trend test P<0.001.However,a nonlinear relationship existed between BMI and RHR.The regression coefficient was-0.70(95%CI-0.93--0.48,P<0.001)after BMI<27.6 kg/m2 adjustment,while which was 0.11(95%CJ-0.37-0.59,P=0.649)for BMI ≥27.6 kg/m2.Conclusion BMI has significantly negative correlation with RHR at admission in the patients with CHD,and the saturation effect exists.

Body mass indexObesityHeart rateCoronary heart disease

黄琼芳、潘燕彬、颜建龙

展开 >

深圳市人民医院/暨南大学第二临床医学院/南方科技大学第一附属医院健康管理科,广东深圳 518020

深圳市人民医院/暨南大学第二临床医学院/南方科技大学第一附属医院心血管内科/深圳市心血管微创医学工程技术研究开发中心,广东 深圳 518020

体重指数 肥胖 心率 冠心病

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(1)
  • 29