首页|NLR及PLR检测在儿童肺炎支原体感染中的诊断及预后价值

NLR及PLR检测在儿童肺炎支原体感染中的诊断及预后价值

扫码查看
目的 探讨中性粒细胞/淋巴细胞比值(NLR)和血小板/淋巴细胞比值(PLR)在小儿肺炎支原体(MP)感染中的诊断和预后价值。方法 采用回顾性分析,以2023年1-6月肺炎支原体抗体-免疫球蛋白M(MP-IgM)阳性患儿100例为病例组,同期抽取健康患儿100例为对照组;再以病例组患儿首次复查结果为准,分为未恢复组(MP-IgM阳性)和已恢复组(MP-IgM阴性);将各组NLR、PLR水平进行比较,建立logistic回归模型,利用受试者的工作特征曲线(ROC曲线)对二者的诊断价值进行分析。结果 病例组NLR、PLR水平显著高于对照组(P<0。05);NLR、PLR单独和联合检测诊断儿童MP感染的曲线下面积(AUC)分别为0。749、0。701和0。758,联合检测AUC最大,对应灵敏度为83。00%,特异度为61。00%(P<0。001)。未恢复组NLR和PLR水平也较已恢复组明显提高(P<0。05)。结论 NLR、PLR与MP感染联系密切,联合检测对MP感染的预测灵敏度更高,两者对患儿预后情况也有一定的提示作用。
Diagnostic and prognostic value of NLR and PLR detection in children with mycoplasma pneumonia infection
Objective To investigate the diagnostic and prognostic value of neutrophil/lymphocyte ratio(NLR)and platelet/lymphocyte ratio(PLR)in children with mycoplasma pneumonia(MP)infection.Methods The retrospective analysis was adopted.One hundred children patients with MP-IgM positive from January to June 2023 served as the case group,and other 100 healthy children during the same period were ex-tracted as the control group;the results of the first re-examination in the case group served as the standard,the children patients in the case group were divided into the unrecovered group(MP-IgM positive)and the re-covered group(MP-IgM negative);the levels of NLR and PLR were compared among the groups,and the lo-gistic regression model was established,then the receiver operating characteristic(ROC)curve was used to an-alyze the diagnostic value of the two.Results The levels of NLR and PLR in the case group were significantly higher than those in the control group(P<0.05);the areas under the curve(AUC)of single detection and combined detection of NLR and PLR in the diagnosis of the children patients with MP infection were 0.749,0.701 and 0.758 respectively.AUC of the combined detection was maximal,the corresponding sensitivity was 83.00%and the specificity was 61.00%(P<0.001).The levels of NLR and PLR in the unrecovered group were also significantly increased compared with those in the recovered group(P<0.05).Conclusion NLR and PLR are closely correlated to MP infection,and their combined detection has the higher sensitivity for MP in-fection and the both also have a certain prompt effect on the prognosis in the children patients.

Mycoplasma pneumoniaDiagnosisPrognosisNeutrophil to lymphocyte ratioPlatelet to lymphocyte ratio

王丽娟、朵俊、张紫薇、王红红、云发超

展开 >

乌鲁木齐市中医医院检验科,新疆乌鲁木齐 830000

乌鲁木齐市友谊医院检验科,新疆 乌鲁木齐 830000

新疆军区总医院中西医结合科,新疆 乌鲁木齐 830000

肺炎支原体 诊断 预后 中性粒细胞/淋巴细胞比值 血小板/淋巴细胞比值

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(1)
  • 23