首页|股骨头坏死合并HIV感染患者行全髋关节置换术的临床研究

股骨头坏死合并HIV感染患者行全髋关节置换术的临床研究

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目的 探讨股骨头坏死(ONFH)合并人类免疫缺陷病毒(HIV)感染者行全髋关节置换术的安全性。方法 选取2021年1月至2022年12月在该院骨科行全髋关节置换术的ONFH患者55例,其中HIV感染者24例(HIV-ONFH组),非HIV感染者31例(NHIV-ONFH组)。比较2组红细胞比容(Hct)水平、总失血量(TBL)、显性失血量(DBL)、隐性失血量(HBL)、输血率、手术时间、髋关节功能Harris评分及并发症发生情况。结果 2组术前及术后血红蛋白(Hb)、Hct水平及Hb下降值比较,差异均无统计学意义(P>0。05)。2组TBL、输血率及术后1周Harris评分比较,差异无统计学意义(P>0。05)。2组DBL、HBL及手术时间比较,差异有统计学意义(P<0。05)。2组住院期间均未出现相关并发症,术后疼痛缓解和功能恢复良好。结论 ONFH合并HIV感染者行全髋关节置换术是安全有效的,不会增加出血风险。
Clinical study on total hip replacement in patients with osteonecrosis of the femoral head combined with HIV infection
Objective To explore the safety of total hip arthroplasty in patients with osteonecrosis of the femoral head(ONFH)combined with human immunodeficiency virus(HIV)infection.Methods A total of 55 ONFH patients who underwent total hip replacement in the Orthopedics Department of the hospital from January 2021 to December 2022 were selected,including 24 HIV-infected patients(the HIV-ONFH group)and 31 non-HIV-infected patients(the NHIV-ONFH group).The levels of hematocrit(Hct),total blood loss(TBL),dominant blood loss(DBL),hidden blood loss(HBL),transfusion rate,surgical time,Harris score of hip joint function,and incidence of complications between the two groups were compared.Results There were no statistically significant differences in the levels of HB,Hct,and HB decrease value be-fore and after surgery between the two groups(P>0.05).There were no statistically significant differences in terms of TBL,transfusion rate,and Harris score at one week after surgery between the two groups(P>0.05).There were statistically significant differences in DBL,HBL,and surgical time between the two groups(P<0.05).No related complications occurred during hospitalization in the two groups,and postoperative pain relief and functional recovery were good.Conclusion Total hip replacement for ONFH patients with HIV in-fection is safe and effective,and will not increase the risk of bleeding.

Total hip replacementHuman immunodeficiency virusOsteonecrosis of the femoral head

鲁坤、刘奇、胡佳威、阳春华

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南华大学衡阳医学院长沙市第一医院研究生协作培养基地,湖南长沙 410005

全髋关节置换术 人类免疫缺陷病毒 股骨头坏死

湖南省科学技术厅科技创新计划项目

2020SK53004

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(2)
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