Effects of enteral nutrition support on gastrointestinal protection and Treg/Th17 immune balance in patients with acute myocardial infarction
Objective To explore the impact of enteral nutrition support on patients with acute myo-cardial infarction(AMI).Methods A total of 104 AMI patients in the hospital from March 2020 to March 2021 were selected and randomly divided into the control group(52 cases)and the observation group(52 ca-ses).The control group received parenteral nutrition support,and the observation group received enteral nutri-tion support.The gastrointestinal protection effect,gastrointestinal function recovery,immune balance,inci-dence of complications,and nutritional status were compared between the two groups.Results There were no statistically significant differences in the levels of diamine oxidase(DAO)and D-lactate before intervention be-tween the two groups(P＞0.05).After intervention,the levels of DAO and D-lactate in the two groups were lower than those before intervention,and the indicators in the observation group were lower than those in the control group,and the differences were statistical significance(P＜0.05).The remission time of nausea and vomiting,the remission time of diarrhea,the recovery time of oral feeding and the recovery time of bowel sounds in the observation group were shorter than those in the control group,and the differences were statisti-cally significant(P＜0.05).There was no statistically significant difference in Th17,Treg levels,and Th17/Treg ratio before intervention between the two groups(P＞0.05).After intervention,the levels of Th17,Treg and Th17/Treg values in the observation group were significantly different from those in the control group(P＜0.05).There was statistically significant difference in the incidence of complications between the two groups(P＜0.05).There were no statistically significant differences in the levels of albumin,hemoglobin,transferrin,and prealbumin before intervention between the two groups(P＞0.05).After intervention,the levels of albumin,hemoglobin,transferrin,and prealbumin in the two groups were higher than those before in-tervention,and the indicators in the observation group were higher than those in the control group,and the differences were statistically significant(P＜0.05).Conclusion Enteral nutrition support can enhance the protection of gastrointestinal tract in AMI patients,promote the rapid recovery of gastrointestinal function,improve the immune and nutritional status,and reduce the incidence of complications.
Acute myocardial infarctionEnteral nutrition supportComplicationsGastrointes-tinal function
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