Influence of marital status on survival of pancreatic cancer patients
Objective To explore the influence of different marital status on cancer-specific survival(CSS)of pancreatic cancer patients.Methods The clinical data of pancreatic cancer patients from 2004 to 2016 were obtained from the SEER database.The patients were grouped according to different marital status,age,TNM stage and surgical conditions.Multivariate COX regression model was used to analyze the influence of marital status on CSS of pancreatic cancer patients.Results There were statistically significant differences in median CSS among patients with different marital status,age,race,TNM stage,Grade classification,and surgical status(P<0.01).Marital status,age,Grade classification,TNM stage and operation were independent influencing factors of CSS in pancreatic cancer patients(P<0.01).In the age group of<60 and ≥60 years old,marital status was an independent influencing factor of CSS in pancreatic cancer patients(P<0.05).In the non-surgical group,marital status were independent influencing factors for CSS in pancreatic cancer patients(P<0.05).In the surgical group,marital status was not independent factor affecting CSS in pancreatic cancer patients(P>0.05).In the phase Ⅲ and Ⅳ groups,marital status was an independent influencing factor of CSS in pancreatic cancer patients(P<0.05).In the stage Ⅰ and Ⅱ groups,marital status was not an independent influencing factor for CSS in pancreatic cancer patients(P>0.05).Conclusion Marital status is related to the prognosis of pancreatic cancer patients.The CSS of married patients is better than that of unmarried and poor married patients.