首页|肠道菌群与食管癌免疫治疗的研究进展

肠道菌群与食管癌免疫治疗的研究进展

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胃肠道中特定细菌和菌群失调与肿瘤发生、发展密切相关.目前,免疫治疗在食管癌治疗领域取得了重要进展,为部分食管癌患者带来了新希望.然而,食管癌免疫治疗疗效受诸多因素影响,如肠道菌群.因此,调节微生物水平,使微生物群在肠道富集,可能会达到提高食管癌免疫治疗疗效的 目的.该文对肠道菌群在食管癌发生发展中的作用及其对肿瘤免疫治疗疗效影响等研究进行了综述.
Research progress on intestinal microflora and immunotherapy for esophageal cancer
Specific bacteria and dysbacteriosis in the gastrointestinal tract are closely related to the oc-currence and development of tumors.At present,immunotherapy has made significant progress in the field of esophageal cancer treatment,bringing new hope to some esophageal cancer patients.However,the efficacy of immunotherapy for esophageal cancer is influenced by many factors,such as intestinal microflora.Therefore,regulating the level of microorganisms and enriching the microbiota in the intestine may achieve the goal of improving the efficacy of immunotherapy for esophageal cancer.The article reviews the role of gut microbiota in the occurrence and development of esophageal cancer,as well as its impact on the efficacy of tumor immu-notherapy.

Intestinal microfloraEsophageal cancerImmune checkpoint inhibitorsImmuno-therapy

张琦、薛丽英

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内蒙古医科大学内蒙古临床医学院,内蒙古呼和浩特 010000

内蒙古自治区人民医院肿瘤内科,内蒙古呼和浩特 010000

肠道菌群 食管癌 免疫检查点抑制剂 免疫治疗

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(2)
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