Study on the effect of comprehensive management of a geriatric hospital on the examination of pathogens before treatment with antibacterial drugs
Objective To evaluate the effect of comprehensive management on pathogen detection be-fore therapeutic use of antibacterial drugs.Methods A total of 20 285 inpatients who used antibacterial drugs for therapeutic purposes in a hospital from January 2020 to December 2022 were selected.Comprehensive management began in January 2022,and comprehensive management began in January 2022.Comprehensive management intervention measures included holding communication and coordination meetings,building an in-formation system,establishing a special action plan,conducting relevant knowledge training,incorporating in-dicators into feedback and quality assessment,etc.The rate of pathogen testing for hospitalized patients,the rate of pathogen testing related to hospital infection diagnosis,the rate of pathogenic examination before the combined use of key drugs,the submission of microbial samples,and the use of antibacterial drugs before(Jan-uary 2022 to December 2022)and after comprehensive management(January 2020 to December 2021)were compared.Results The microbiological sample submission rate for comprehensive management inpatients be-fore therapeutic use of antibiotics was 65.30%(858/1 314),which was higher than 59.66%(247/414)and 57.82%(122/211)in 2021 and 2020 before intervention;The detection of pathogens before treatment with re-stricted grade antibiotics increased from 92.79%(3 129/3 372)and 93.52%(2 843/3 040)before comprehen-sive management to 97.01%(3 404/3 509)after comprehensive management;The rate of submitting microbi ological samples for diagnosis of hospital infection increased from 58.60%(109/186)and 77.78%(140/180)before intervention to 91.52%(151/165)after intervention,with significant differences(P<0.05);Before and after comprehensive management,there were no significant differences in the rates of pathogen testing,sterile specimen testing,and antibacterial drug use(P>0.05);The overall positive rate of specimens decreased.Con-clusion Comprehensive intervention measures can effectively and synchronously improve the rate of pathogen testing before therapeutic use of antibacterial drugs and the rate of pathogen testing related to hospital infec-tion diagnosis.
Before therapeutic use of antibacterial drugsComprehensive managementPathogenic test submission rateEffect study