Apolipoprotein B and acute coronary syndrome:a review
Apolipoprotein B is an important protein directly involved in the atherosclerotic process and is closely related to the occurrence of cardiovascular events.Acute coronary syndrome is a clinical syndrome based pathologically on the rupture of a coronary atherosclerotic plaque followed by complete or incomplete occlusive thrombosis triggering acute ischemia or necrosis of the myocardium.Studies have shown a more comprehensive coverage of atherogenic particles by apolipoprotein B,which is expected to be a powerful pre-dictor of acute coronary syndrome risk and prognosis.In this review,we summarize the structure of apoB,the mechanisms and processes involved in the development and progression of ACS,the corresponding prevention,treatment,and research.
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