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影响热射病患者90 d预后的危险因素分析

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目的 探讨热射病患者90 d预后的危险因素。方法 回顾性分析2018年6月至2022年8月该院重症医学科收治的热射病患者89例,根据90 d死亡情况分为存活组(62例)和死亡组(27例),比较2组患者年龄、入院时体温及心率、降温时间、炎症及器官功能障碍的实验室数据、急性生理和慢性健康状况Ⅱ评分、序贯器官衰竭估计(SOFA)评分、格拉斯哥昏迷评分法评分等。结果 89例患者中90 d内死亡27例(30。3%)。降温时间、入院时心率、SOFA评分是影响患者生存的独立危险因素(风险比=6。230、1。738、1。042,95%可信区间:2。561~14。521、1。026~2。114、1。011~1。427,P=0。004、0。002、0。023)。降温时间、入院时心率、SOFA评分联合预测热射病患者90 d病死率的受试者工作特征曲线下面积为0。993(95%可信区间:0。976~1。000,P<0。001),灵敏度为1。000,特异度为0。933。结论 降温时间、入院时心率、SOFA评分是影响热射病患者90 d生存的因素,3个指标可联合使用预测患者90 d病死率和不良预后。
Analysis of risk factors affecting 90-day prognosis of patients with heat stroke
Objective To investigate the risk factors of 90-day prognosis in patients with heat stroke.Methods A retrospective analysis was performed on 89 patients with heat stroke admitted to the Department of Intensive Care Medicine,Mianyang Central Hospital from June 2018 to August 2022.They were divided in-to the survival group and the death group according to 90-day mortality.Data of age,temperature and heart rate at admission,cooling time,inflammation and laboratory data on organ dysfunction,acute physiology and chronic health evaluation Ⅱ score,Sequential Organ Failure Assessment(SOFA)score,and Glasgow Coma Scale score were compared between the two groups.Results Of the 89 patients,27(30.3%)died within 90 days.Cooling time,heart rate at admission,SOFA score were independent risk factors affecting patient surviv-al,and the differences were statistically significant(HR=6.230,1.738,1.042,95%confidence interval:2.561-14.521,1.026-2.114,1.011-1.427,P=0.004,0.002,0.023).The area under the working charac-teristic curve of the combination of cooling time,heart rate at admission,and SOFA score predicted the 90-day mortality of the patients with heat stroke was 0.993(95%CI:0.976-1.000,P<0.001),the sensitivity was 1.000,and the specificity was 0.933.Conclusion Cooling time,heart rate on admission,and SOFA score are the factors affecting 90-day survival of patients with thermal radiation.The three indexes can be used in com-bination to predict 90-day mortality and poor prognosis.

Heat strokeCritical illnessRisk factorsPrognosisCase fatality rate

徐榕、文丹、何海燕、杜小利

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电子科技大学医学院附属绵阳医院/绵阳市中心医院重症医学科,四川绵阳 621000

中暑 危重病 危险因素 预后 病死率

绵阳市中心医院院内护理科研课题

MCHHL2023YB05

2024

现代医药卫生
重庆市卫生信息中心

现代医药卫生

影响因子:0.758
ISSN:1009-5519
年,卷(期):2024.40(4)
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