Application of different ultrasonic elastography in evaluating early atherosclerosis in patients with chronic kidney disease
Objective To explore the application value of real-time shear wave elastography(SWE)and ultrafast pulse wave velocity(ufPWV)in evaluating early atherosclerosis in patients with chronic kidney dis-ease(CKD).Methods A total of 135 patients with CKD diagnosed in Ningbo Second Hospital from August 2019 to August 2022 were selected as the case group,and 50 healthy people with normal renal function were selected as the control group.The case group and the control group were divided into three groups according to age(＜45 years old,45-60 years old,＞60 years old).The patients in the case group were divided into G1 stage group,G2 stage group,G3a stage group,and G3b stage group according to the glomerular filtration rate.The mean elastic Young's modulus(a-MEmean)of the anterior wall and the mean elastic Young's modulus(p-MEmean)of the posterior wall of the common carotid artery were measured by SWE technique.The pulse wave velocity(PWV-BS)at the beginning of the systolic period and the pulse wave velocity(PWV-ES)at the end of the systolic period of the common carotid artery were measured by ufPWV technique.Results The a-MEmean,p-MEmean,PWV-BS and PWV-ES of the common carotid artery wall in the case group were sig-nificantly higher than those in the control group,and the differences were statistically significant(P＜0.05).The a-MEmean,p-MEmean,PWV-BS and PWV-ES of carotid artery wall in CKD were positively correlated with age(r=0.352,0.390,0.236,0.218,P＜0.05),and negatively correlated with glomerular filtration rate(r=-0.517,-0.585,-0.515,-0.430,P＜0.05).Conclusion Both SWE and ufPWV can accurately evalu-ate the early longitudinal and circumferential stiffness changes of carotid artery vessel wall in CKD patients,which can provide valuable information for clinical diagnosis and treatment.
万方数据
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